伴有多内分泌腺病的自身免疫性早发性卵巢功能衰竭及卵巢滤泡活性的自发恢复。
Autoimmune premature ovarian failure with polyendocrinopathy and spontaneous recovery of ovarian follicular activity.
作者信息
Tan S L, Hague W M, Becker F, Jacobs H S
出版信息
Fertil Steril. 1986 Mar;45(3):421-4. doi: 10.1016/s0015-0282(16)49229-0.
PMID:3949043
Abstract
Premature ovarian failure accounts for 10% of cases of secondary amenorrhea, and in most cases its cause remains unknown. One mechanism by which it occurs is autoimmune destruction. A 21-year-old patient is described in whom autoimmune ovarian failure occurred in association with Addison's disease and primary hypothyroidism. Although premature ovarian failure is generally considered irreversible, the patient subsequently resumed spontaneous ovarian follicular activity.
摘要
卵巢早衰占继发性闭经病例的10%，在大多数情况下其病因尚不清楚。其发生的一种机制是自身免疫性破坏。本文描述了一名21岁的患者，其自身免疫性卵巢衰竭与艾迪生病和原发性甲状腺功能减退症相关。虽然卵巢早衰通常被认为是不可逆的，但该患者随后恢复了自发的卵巢卵泡活动。
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