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初次全髋关节置换术比翻修全髋关节置换术更快达到最小临床重要差异。

Primary Total Hip Arthroplasty Achieves Minimal Clinically Important Difference Faster than Revision Total Hip Arthroplasty.

作者信息

Lim Perry L, Wang Kevin Y, Bedair Hany S, Melnic Christopher M

机构信息

Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Department of Orthopaedic Surgery, Newton-Wellesley Hospital, Newton, Massachusetts.

出版信息

J Arthroplasty. 2025 Apr;40(4):941-947. doi: 10.1016/j.arth.2024.10.002. Epub 2024 Oct 26.

Abstract

BACKGROUND

Despite the prevalence of total hip arthroplasty (THA) as a treatment for hip-related conditions, there is limited research directly comparing the patient-reported outcome measures between primary and revision total hip arthroplasty (rTHA). This study compared the time to achieve minimal clinically important difference (MCID) between primary and rTHA.

METHODS

We conducted a retrospective analysis comparing 6,671 THAs (6,070 primary and 601 all-cause rTHAs) performed between 2016 and 2022. Patient-reported outcomes were evaluated using preoperative and postoperative scores of Patient-Reported Outcomes Measurement Information System (PROMIS) Global Physical, PROMIS Physical Function Short Form 10a (PF-10a), and Hip Injury and Osteoarthritis Outcome Score - Physical Function Short Form (HOOS-PS). The time to achieve MCID was assessed using survival curves with and without interval-censoring, and statistical comparisons were performed using log-rank and weighted log-rank tests.

RESULTS

Comparing the time to achieve MCID without interval-censoring, primary total hip arthroplasty (pTHA) demonstrated significantly faster median times than rTHA for PROMIS Global Physical (3.3 versus 3.9 months, P < 0.001), PROMIS PF-10a (3.6 versus 6.2 months, P < 0.001), and HOOS-PS (3.1 versus 4.0 months, P < 0.001). Similarly, when using interval-censoring, pTHA continued to achieve MCID significantly faster than rTHA for PROMIS Global Physical (0.23 to 0.24 versus 0.50 to 0.51 months, P < 0.001), PROMIS PF-10a (1.43 to 1.44 versus 3.03 to 3.04 months, P < 0.001), and HOOS-PS (0.87 to 0.87 versus 1.20 to 1.21 months, P < 0.001).

CONCLUSIONS

Across all patient-reported outcome measures, pTHA achieved MCID significantly faster than rTHA, irrespective of interval-censoring. These findings underscore the importance of setting realistic postoperative recovery expectations during perioperative patient counseling. Future studies should investigate the factors influencing time to achieve MCID and explore how to enhance rTHA techniques and perioperative management for improved patient outcomes.

LEVEL OF EVIDENCE

III.

摘要

背景

尽管全髋关节置换术(THA)作为髋关节相关疾病的一种治疗方法很普遍,但直接比较初次全髋关节置换术和翻修全髋关节置换术(rTHA)患者报告的结局指标的研究有限。本研究比较了初次和rTHA达到最小临床重要差异(MCID)的时间。

方法

我们进行了一项回顾性分析,比较了2016年至2022年期间进行的6671例THA(6070例初次置换和601例全因翻修)。使用患者报告结局测量信息系统(PROMIS)总体身体状况、PROMIS身体功能简表10a(PF-10a)以及髋关节损伤和骨关节炎结局评分-身体功能简表(HOOS-PS)的术前和术后评分来评估患者报告的结局。使用有和没有区间删失的生存曲线评估达到MCID的时间,并使用对数秩检验和加权对数秩检验进行统计比较。

结果

在不进行区间删失的情况下比较达到MCID的时间,初次全髋关节置换术(pTHA)在PROMIS总体身体状况(3.3个月对3.9个月,P<0.001)、PROMIS PF-10a(3.6个月对6.2个月,P<0.001)和HOOS-PS(3.1个月对4.0个月,P<0.001)方面的中位时间显著快于rTHA。同样,在使用区间删失时,pTHA在PROMIS总体身体状况(0.23至0.24个月对0.50至0.51个月,P<0.001)、PROMIS PF-10a(1.43至1.44个月对3.03至3.04个月,P<0.001)和HOOS-PS(0.87至0.87个月对1.20至1.21个月,P<0.001)方面达到MCID的速度仍显著快于rTHA。

结论

在所有患者报告的结局指标中,无论是否进行区间删失,pTHA达到MCID的速度均显著快于rTHA。这些发现强调了在围手术期患者咨询过程中设定现实的术后恢复预期的重要性。未来的研究应调查影响达到MCID时间的因素,并探索如何改进rTHA技术和围手术期管理以改善患者结局。

证据级别

III级。

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