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初发转移性激素敏感性前列腺癌(mHSPC)的管理及放射治疗的作用:意大利放射治疗与临床肿瘤学会(AIRO)的共识

Management of de Novo Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) and the Role of Radiation Therapy: A Consensus by the Italian Association of Radiotherapy and Clinical Oncology (AIRO).

作者信息

Lancia Andrea, Alitto Anna Rita, Pappagallo Giovanni, Ciurlia Elisa, Francolini Giulio, D'Angelillo Rolando, Fersino Sergio, Levra Niccolò Giaj, Jereczek-Fossa Barbara Alicja, Magli Alessandro, Pasqualetti Francesco, Reali Alessia, Spatola Corrado, Triggiani Luca

机构信息

Department of Radiation Oncology, Policlinico San Matteo Pavia Fondazione IRCCS, Pavia, Italy.

UOC di Radioterapia Oncologica, Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Rome, Italy.

出版信息

Pract Radiat Oncol. 2025 May-Jun;15(3):e286-e294. doi: 10.1016/j.prro.2024.10.007. Epub 2024 Oct 28.

Abstract

PURPOSE

Prostate cancer treatments paradigms are in continuous evolution, especially in the metastatic setting. In this context, the Genito-Urinary Group of Italian Association of Radiotherapy and Clinical Oncology aimed to create a consensus on radiation therapy indication in de novo metastatic hormone-sensitive prostate cancer both on primary tumor and metastatic sites.

METHODS

A panel of experts, involved in clinical management of prostate cancer, through the estimate-talk-estimate method, developed a list of items and correspondent statements on the identified topic.

RESULTS

Seven conclusive items were identified with 12 statements about the chosen topic, radiation therapy in metastatic hormone-sensitive prostate cancer on primary tumor and metastatic sites.

CONCLUSIONS

This consensus might help clinicians in prostate cancer managing in daily clinical practice.

摘要

目的

前列腺癌的治疗模式在不断演变,尤其是在转移性疾病的治疗方面。在此背景下,意大利放射治疗与临床肿瘤学会泌尿生殖组旨在就初治转移性激素敏感性前列腺癌原发肿瘤和转移部位的放射治疗适应证达成共识。

方法

一个参与前列腺癌临床管理的专家小组通过“评估-讨论-评估”方法,制定了一份关于已确定主题的条目及相应声明清单。

结果

确定了七个结论性条目,包含12条关于选定主题(转移性激素敏感性前列腺癌原发肿瘤和转移部位的放射治疗)的声明。

结论

这一共识可能有助于临床医生在日常临床实践中管理前列腺癌。

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