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神经类黑色素沉着病——来自印度南部一家三级医疗中心的13例病例回顾性研究

Neuromelioidosis - A retrospective review of thirteen cases from a tertiary care centre from South India.

作者信息

Vithiya G, Rajalakshmi Preethi G, Sundaram P Shunmuga, Rajendran T

机构信息

Department of Microbiology, Velammal Medical College Hospital and Research Institute, Madurai, India.

Department of Radiodiagnosis, Velammal Medical College Hospital and Research Institute, Madurai, India.

出版信息

Indian J Med Microbiol. 2024 Nov-Dec;52:100751. doi: 10.1016/j.ijmmb.2024.100751. Epub 2024 Nov 5.

Abstract

Neurologic melioidosis warrants attention in view of its rarity and lethal consequences. We performed a retrospective review of culture confirmed neurologic melioidosis reported between 2017 and 2023. Thirteen patients were identified with median age 43 years and all but three were males. Brain parenchyma was involved in 57 % cases (7/13) as cerebritis, encephalitis and macro abscess or micro abscess. Three patients had myelitis with spinal cord micro abscess and cerebral venous thrombosis in three other patients. Five patients died during hospitalization. Two were discharged against medical advice due to financial constraints. Six survivors were followed between one and eight months.

摘要

鉴于神经型类鼻疽病的罕见性及其致命后果,值得关注。我们对2017年至2023年期间报告的经培养确诊的神经型类鼻疽病进行了回顾性研究。确定了13例患者,中位年龄43岁,除3例女性外均为男性。57%的病例(7/13)脑实质受累,表现为脑炎、脑脓肿或微脓肿。3例患者患有脊髓炎伴脊髓微脓肿,另外3例患者患有脑静脉血栓形成。5例患者在住院期间死亡。2例因经济困难自动出院。6名幸存者随访了1至8个月。

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