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加勒比地区非洲裔基因混合与血压变化之间的关系。

Relationship between African admixture and blood pressure variation in the Caribbean.

作者信息

Hutchinson J

出版信息

Hum Hered. 1986;36(1):12-8. doi: 10.1159/000153593.

Abstract

The genetic contribution to blood pressure variance is examined by studying a selected group of genes. Of 368 individuals, 48.1% received one-half or more of their genes from an African ancestor and of this group 18.1 and 17.0% exhibit systolic and diastolic hypertension, respectively. A chi-square test was used to examine the dependence of blood pressure on percentage African ancestry. The chi-square values were not significant for systolic or diastolic pressures. It is likely that other factors are strongly related to African admixture and these factors are the true modifiers of blood pressure.

摘要

通过研究一组选定的基因来检测基因对血压变异的贡献。在368名个体中,48.1%的个体其一半或更多的基因来自非洲祖先,在这一组中,分别有18.1%和17.0%的个体表现出收缩期和舒张期高血压。使用卡方检验来检测血压对非洲血统百分比的依赖性。收缩压或舒张压的卡方值并不显著。很可能其他因素与非洲血统混合密切相关,而这些因素才是血压的真正调节因子。

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