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高分辨率磁共振成像在椎动脉夹层诊断与治疗中的应用:一例报告

High-resolution magnetic resonance imaging in the diagnosis and management of vertebral artery dissection: A case report.

作者信息

Zhang Hai-Bin, Duan Yong-Hong, Zhou Min, Liang Ri-Chu

机构信息

Department of Neurosurgery, The Leiyang City People's Hospital, Hengyang 421001, Hunan Province, China.

Department of Neurosurgery, The Second Affiliated Hospital of University of South China, Hengyang 421001, Hunan Province, China.

出版信息

World J Radiol. 2024 Oct 28;16(10):593-599. doi: 10.4329/wjr.v16.i10.593.

Abstract

BACKGROUND

Vertebral artery dissection (VAD) is a rare but life-threatening condition characterized by tearing of the intimal layer of the vertebral artery, leading to stenosis, occlusion or rupture. The clinical presentation of VAD can be heterogeneous, with common symptoms including headache, dizziness and balance problems. Timely diagnosis and treatment are crucial for favorable outcomes; however, VAD is often missed due to its variable clinical presentation and lack of robust diagnostic guidelines. High-resolution magnetic resonance imaging (HRMRI) has emerged as a reliable diagnostic tool for VAD, providing detailed visualization of vessel wall abnormalities.

CASE SUMMARY

A young male patient presented with an acute onset of severe headache, vomiting, and seizures, followed by altered consciousness. Imaging studies revealed bilateral VAD, basilar artery thrombosis, multiple brainstem and cerebellar infarcts, and subarachnoid hemorrhage. Digital subtraction angiography (DSA) revealed vertebral artery stenosis but failed to detect the dissection, potentially because intramural thrombosis obscured the VAD. In contrast, HRMRI confirmed the diagnosis by revealing specific signs of dissection. The patient was managed conservatively with antiplatelet therapy and other supportive measures, such as blood pressure control and pain management. After 5 mo of rehabilitation, the patient showed significant improvement in swallowing and limb strength.

CONCLUSION

HR-MRI can provide precise evidence for the identification of VAD.

摘要

背景

椎动脉夹层(VAD)是一种罕见但危及生命的疾病,其特征是椎动脉内膜层撕裂,导致狭窄、闭塞或破裂。VAD的临床表现可能多种多样,常见症状包括头痛、头晕和平衡问题。及时诊断和治疗对于取得良好预后至关重要;然而,由于其临床表现多变且缺乏有力的诊断指南,VAD常常被漏诊。高分辨率磁共振成像(HRMRI)已成为VAD的可靠诊断工具,可详细显示血管壁异常情况。

病例摘要

一名年轻男性患者急性起病,出现严重头痛、呕吐和癫痫发作,随后意识改变。影像学检查显示双侧VAD、基底动脉血栓形成、多发脑干和小脑梗死以及蛛网膜下腔出血。数字减影血管造影(DSA)显示椎动脉狭窄,但未能检测到夹层,可能是因为壁内血栓掩盖了VAD。相比之下,HRMRI通过显示夹层的特定征象确诊。患者接受了抗血小板治疗及其他支持措施,如血压控制和疼痛管理等保守治疗。经过5个月的康复治疗,患者吞咽功能和肢体力量有显著改善。

结论

HR-MRI可为VAD的识别提供精确依据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2570/11525835/9c227dc09976/WJR-16-593-g001.jpg

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