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胆囊血吸虫病

Gallbladder schistosomiasis.

作者信息

Del Angel-Millán Gabriela, Jukemura José, Bicudo Júlia Bragion, Jureidini Ricardo, Montagnini André Luís, Segatelli Vanderlei, Ribeiro Thiago Costa, Namur Guilherme Naccache, Costa Thiago Nogueira, Stolzemburg Lucas Cata Preta, Abdo Emilio Elias, Ribeiro Ulysses, Herman Paulo, Figueira Estela Regina Ramos

机构信息

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Departamento de Gastroenterologia e Nutrologia, Divisão de Cirurgia do Aparelho Digestivo, São Paulo, SP, Brasil.

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Departamento de Patologia, São Paulo, SP, Brasil.

出版信息

Autops Case Rep. 2024 Oct 8;14:e2024516. doi: 10.4322/acr.2024.516. eCollection 2024.

DOI:10.4322/acr.2024.516
PMID:39494156
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11529890/
Abstract

Schistosomiasis is an infectious disease caused by parasitic flatworms of the genus Schistosoma. The species is associated with hepatosplenic disease. Schistosomiasis involving the gallbladder alone is highly unusual, with a few cases reported. Herein, we present the case of a woman from a region with endemic schistosomiasis who presented with a painless solid lesion and wall thickening of the gallbladder. She underwent an uneventful laparoscopic cholecystectomy. Microscopic examination of the surgical specimen revealed eggs associated with granulomatous reaction, leading to the diagnosis of schistosomiasis of the gallbladder, prompting subsequent treatment with praziquantel and follow-up. This case illustrates the importance of suspicion for this diagnosis in endemic areas, as it can be misdiagnosed with malignancy if not examined microscopically. Complications and treatment strategies are poorly characterized for the few cases of schistosomiasis; reporting this case can serve as a helpful reminder of a rare presentation of this disease.

摘要

血吸虫病是一种由血吸虫属寄生扁虫引起的传染病。该物种与肝脾疾病有关。仅累及胆囊的血吸虫病非常罕见,仅有少数病例报道。在此,我们报告一例来自血吸虫病流行地区的女性病例,该患者表现为胆囊无痛性实性病变和胆囊壁增厚。她接受了顺利的腹腔镜胆囊切除术。手术标本的显微镜检查发现虫卵伴有肉芽肿反应,从而诊断为胆囊血吸虫病,随后给予吡喹酮治疗并进行随访。该病例说明了在流行地区怀疑这种诊断的重要性,因为如果不进行显微镜检查,可能会误诊为恶性肿瘤。对于少数血吸虫病病例,并发症和治疗策略的特征尚不明确;报告该病例有助于提醒人们注意这种疾病的罕见表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/365b/11529890/533b6f3724d8/autopsy-14-e2024516-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/365b/11529890/4364aa718fa7/autopsy-14-e2024516-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/365b/11529890/533b6f3724d8/autopsy-14-e2024516-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/365b/11529890/4364aa718fa7/autopsy-14-e2024516-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/365b/11529890/533b6f3724d8/autopsy-14-e2024516-g02.jpg

相似文献

1
Gallbladder schistosomiasis.胆囊血吸虫病
Autops Case Rep. 2024 Oct 8;14:e2024516. doi: 10.4322/acr.2024.516. eCollection 2024.
2
Gall bladder schistosomiasis diagnosed incidentally post laparoscopic cholecystectomy: A case report.腹腔镜胆囊切除术后偶然诊断出的胆囊血吸虫病:一例报告。
Int J Surg Case Rep. 2023 Sep;110:108787. doi: 10.1016/j.ijscr.2023.108787. Epub 2023 Sep 2.
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Rare presentation of gallbladder schistosomiasis: a case report.罕见的胆囊血吸虫病表现:一例报告。
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Ultrasonography of gallbladder abnormalities due to schistosomiasis.血吸虫病所致胆囊异常的超声检查
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Gallbladder schistosomiasis: rare but possible, a case report and review of the literature.胆囊血吸虫病:罕见但有可能,一例病例报告及文献复习
Pan Afr Med J. 2019 Feb 26;32:91. doi: 10.11604/pamj.2019.32.91.17907. eCollection 2019.
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Large Mediastinal Mass as a Rare Presentation of Schistosomiasis.巨大纵隔肿块为少见的血吸虫病表现。
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[Schistosomiasis in areas of low endemicity: an overly neglected disease. The example of in BrazilEsquistossomose em áreas de baixa endemicidade, uma doença muito negligenciada. O exemplo de no Brasil].低流行地区的血吸虫病:一种被过度忽视的疾病。以巴西的情况为例 低流行地区的血吸虫病,一种被严重忽视的疾病。巴西的例子
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Hepatosplenic schistosomiasis mansoni: ultrasound manifestations.曼氏血吸虫病肝脾型:超声表现
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Evolution of schistosomiasis-induced pathology after therapy and interruption of exposure to schistosomes: a review of ultrasonographic studies.治疗后及停止接触血吸虫后血吸虫病所致病理变化的演变:超声研究综述
Acta Trop. 2000 Oct 23;77(1):111-31. doi: 10.1016/s0001-706x(00)00125-x.
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Urinary schistosomiasis presented as bladder malignancy with pulmonary metastases: a case report.以膀胱恶性肿瘤伴肺转移表现的泌尿生殖系统血吸虫病:一例报告
Ann R Coll Surg Engl. 2018 Jul;100(6):e145-e146. doi: 10.1308/rcsann.2018.0072.

本文引用的文献

1
Hepatosplenic schistosomiasis: an uncommon cause of liver disease in developed countries.肝脾血吸虫病:发达国家中一种不常见的肝病病因。
Rev Esp Enferm Dig. 2024 Oct;116(10):566-567. doi: 10.17235/reed.2023.10036/2023.
2
Gall bladder schistosomiasis diagnosed incidentally post laparoscopic cholecystectomy: A case report.腹腔镜胆囊切除术后偶然诊断出的胆囊血吸虫病:一例报告。
Int J Surg Case Rep. 2023 Sep;110:108787. doi: 10.1016/j.ijscr.2023.108787. Epub 2023 Sep 2.
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Misdiagnosis of Hepatosplenic Schistosomiasis as Hepatic Tuberculosis: A Case Report.
肝脾型血吸虫病误诊为肝结核:一例报告
Cureus. 2023 Feb 19;15(2):e35169. doi: 10.7759/cureus.35169. eCollection 2023 Feb.
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Gallbladder schistosomiasis displaying as gallbladder perforation: A case report.表现为胆囊穿孔的胆囊血吸虫病:一例报告
Asian J Surg. 2022 Oct;45(10):1958-1959. doi: 10.1016/j.asjsur.2022.04.026. Epub 2022 Apr 19.
5
Effect of preventive chemotherapy with praziquantel on schistosomiasis among school-aged children in sub-Saharan Africa: a spatiotemporal modelling study.在撒哈拉以南非洲地区,用吡喹酮进行预防化疗对学龄儿童血吸虫病的影响:时空建模研究。
Lancet Infect Dis. 2022 Jan;22(1):136-149. doi: 10.1016/S1473-3099(21)00090-6. Epub 2021 Dec 2.
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gallbladder polyp masquerading as a neoplasm: Rare case report and literature review.伪装成肿瘤的胆囊息肉:罕见病例报告及文献综述
Clin Case Rep. 2021 Jul 9;9(7):e04420. doi: 10.1002/ccr3.4420. eCollection 2021 Jul.
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Gallbladder schistosomiasis - a rare presentation as gallbladder polyp: a case report.胆囊血吸虫病——一种罕见的胆囊息肉表现:病例报告
Radiol Case Rep. 2020 Jun 29;15(8):1394-1397. doi: 10.1016/j.radcr.2020.06.013. eCollection 2020 Aug.
8
Schistosomiasis: Still a Cause of Significant Morbidity and Mortality.血吸虫病:仍然是导致严重发病和死亡的原因。
Res Rep Trop Med. 2019 Dec 31;10:153-163. doi: 10.2147/RRTM.S204345. eCollection 2019.
9
Schistosomiasis.血吸虫病。
Adv Exp Med Biol. 2019;1154:45-70. doi: 10.1007/978-3-030-18616-6_3.
10
Gallbladder schistosomiasis: rare but possible, a case report and review of the literature.胆囊血吸虫病:罕见但有可能,一例病例报告及文献复习
Pan Afr Med J. 2019 Feb 26;32:91. doi: 10.11604/pamj.2019.32.91.17907. eCollection 2019.