The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Heilongjiang University of Chinese Medicine, Heilongjiang, China.
PeerJ. 2024 Oct 29;12:e18207. doi: 10.7717/peerj.18207. eCollection 2024.
Risk factors for recovery from oculomotor nerve palsy (ONP) after aneurysm surgery explored by meta-analysis.
The PubMed, Embase, web of science, Cochrane library, China Knowledge, Wan fang, and VIP databases were searched for case-control or cohort studies on risk factors of oculomotor nerve palsy recovery after aneurysm surgery, with a cut-off date of 14 February 2024, and data were analyzed using Stata 15.
A total of 12 articles involving 866 individuals were included, meta-analysis results suggesting that gender (OR = 0.75, 95% CI [0.51-1.10]), age (OR = 1.00, 95% CI [0.93-1.07]), aneurysm size (OR = 0.85, 95% CI [-0.71 to 1.01]), treatment time (OR = 1.01, 95% CI [0.91-1.13]) is not a risk factor for recovery of motor nerve palsy after aneurysm surgery. Preoperative complete ONP (OR = 2.27, 95% CI [1.07-4.81]), surgery (OR = 9.88, 95% CI [2.53-38.57]), subarachnoid hemorrhage (OR = 1.29, 95% CI [1.06-1.56]) is a risk factor for recovery of motor nerve palsy after aneurysm surgery.
Based on the results of the studies we included, we found that complete ONP before surgery led to poorer recovery, but patients with post-operative and subarachnoid hemorrhage had better recovery.
通过荟萃分析探讨眼运动神经麻痹（ONP）后动脉瘤手术后恢复的危险因素。
检索 PubMed、Embase、Web of Science、Cochrane 图书馆、中国知识、万方和 VIP 数据库，查找关于动脉瘤手术后眼运动神经麻痹恢复的危险因素的病例对照或队列研究，截止日期为 2024 年 2 月 14 日，使用 Stata 15 进行数据分析。
共纳入 12 篇涉及 866 人的文章，荟萃分析结果表明，性别（OR=0.75，95%CI[0.51-1.10]）、年龄（OR=1.00，95%CI[0.93-1.07]）、动脉瘤大小（OR=0.85，95%CI[0.71-1.01]）、治疗时间（OR=1.01，95%CI[0.91-1.13]）不是动脉瘤手术后运动神经麻痹恢复的危险因素。术前完全性 ONP（OR=2.27，95%CI[1.07-4.81]）、手术（OR=9.88，95%CI[2.53-38.57]）、蛛网膜下腔出血（OR=1.29，95%CI[1.06-1.56]）是动脉瘤手术后运动神经麻痹恢复的危险因素。
基于我们纳入的研究结果，我们发现术前完全性 ONP 导致恢复较差，但术后和蛛网膜下腔出血的患者恢复较好。
