Risk factors for recovery from oculomotor nerve palsy after aneurysm surgery: a meta-analysis.

BACKGROUND

Risk factors for recovery from oculomotor nerve palsy (ONP) after aneurysm surgery explored by meta-analysis.

METHODS

The PubMed, Embase, web of science, Cochrane library, China Knowledge, Wan fang, and VIP databases were searched for case-control or cohort studies on risk factors of oculomotor nerve palsy recovery after aneurysm surgery, with a cut-off date of 14 February 2024, and data were analyzed using Stata 15.

RESULT

A total of 12 articles involving 866 individuals were included, meta-analysis results suggesting that gender (OR = 0.75, 95% CI [0.51-1.10]), age (OR = 1.00, 95% CI [0.93-1.07]), aneurysm size (OR = 0.85, 95% CI [-0.71 to 1.01]), treatment time (OR = 1.01, 95% CI [0.91-1.13]) is not a risk factor for recovery of motor nerve palsy after aneurysm surgery. Preoperative complete ONP (OR = 2.27, 95% CI [1.07-4.81]), surgery (OR = 9.88, 95% CI [2.53-38.57]), subarachnoid hemorrhage (OR = 1.29, 95% CI [1.06-1.56]) is a risk factor for recovery of motor nerve palsy after aneurysm surgery.

CONCLUSION

Based on the results of the studies we included, we found that complete ONP before surgery led to poorer recovery, but patients with post-operative and subarachnoid hemorrhage had better recovery.