Qin Feng, Wang Mingxing, Qiu Jibing, Guo Jinbao
The Changzhou Clinical College of Xuzhou Medical University, Changzhou, Jiangsu, People's Republic of China.
Department of Otorhinolaryngology, Changzhou Third People's Hospital, Changzhou, Jiangsu, People's Republic of China.
Int J Gen Med. 2024 Oct 29;17:4985-4990. doi: 10.2147/IJGM.S487553. eCollection 2024.
To explore the relationship between hyperlipidemia and full-frequency idiopathic sudden sensorineural hearing loss (FFHL).
A total of 145 FFHL patients admitted from September 2021 to May 2024 were analyzed. Eighty-five patients with hyperlipidemia and 60 patients with normal serum lipids statistically analyze the patient's gender, age, onset time, accompanying symptoms, and serum lipids. Measure the pure tone hearing threshold before and after treatment, and calculate the average increase in hearing threshold. Compare the correlation between various factors and prognosis.
The hyperlipidemia group had a higher proportion of males (=0.043) and vertigo (=0.044) compared to the control group, while other information between the two groups lacked statistical significance. Effective patients (n=44) in the hyperlipidemia group showed significant differences in vertigo (=0.020), age (=0.032), and onset (=0.030) compared to ineffective patients (n=41). Analysis showed that these were independent correlated factors affecting prognosis. Other indicators, including serum lipids, have no significance in predicting the prognosis of patients with hyperlipidemia and complete frequency decline in hearing loss.
Patients with hyperlipidemia have higher rates of males and vertigo. The age, onset, and vertigo of patients with hyperlipidemia are related to prognosis, while various lipid indicators are not related to the prognosis of sudden hearing loss.
探讨高脂血症与全频突发性特发性感音神经性听力损失（FFHL）之间的关系。
对2021年9月至2024年5月收治的145例FFHL患者进行分析。其中85例高脂血症患者和60例血脂正常患者，对患者的性别、年龄、发病时间、伴随症状及血脂进行统计学分析。测量治疗前后的纯音听力阈值，并计算听力阈值平均升高值。比较各因素与预后的相关性。
高脂血症组男性比例（=0.043）和眩晕比例（=0.044）高于对照组，而两组间其他信息无统计学意义。高脂血症组有效患者（n = 44）与无效患者（n = 41）相比，在眩晕（=0.020）、年龄（=0.032）和发病（=0.030）方面存在显著差异。分析表明这些是影响预后的独立相关因素。其他指标，包括血脂，在预测高脂血症和全频听力损失下降患者的预后方面无意义。
高脂血症患者男性和眩晕发生率较高。高脂血症患者的年龄、发病及眩晕与预后相关，而各项血脂指标与突发性听力损失的预后无关。
