Han Seung Cheol, Bae Junhyung, Park Jin-A, Lee Ji Ye, Anatriera Sumarsono Raden A, Rhee Chae-Seo, Shim Ye Ji, Han Doo Hee
Department of Otorhinolaryngology-Head & Neck Surgery, Chungnam National University Sejong Hospital, Sejong, Republic of Korea.
Department of Otorhinolaryngology-Head & Neck Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
Laryngoscope. 2025 Apr;135(4):1315-1320. doi: 10.1002/lary.31881. Epub 2024 Nov 4.
The frequency of paranasal sinus fungus balls, a common form of rhinosinusitis, has increased. Although treatment and causative factors have been well investigated, the evolving nature of the fungal balls remains unelucidated. This study aimed to investigate and analyze the changing patterns of fungus balls.
This retrospective study analyzed data from 35 participants selected from a pool of 41,497 patients who underwent brain magnetic resonance imaging (MRI) at a large health care center. The extent of the fungus balls was evaluated by grading them from 1 to 4 based on the MR images. The changing process of the fungus ball was analyzed based on demographics, interval between the MRI scans, comorbidities, and specific dental interventions.
The fungus ball grades showed significant progression over time. In the analysis of 29 sinuses with initially low-grade (grades 0, 1, and 2) fungus balls, 15 sinuses showed a grade change <2 (no/minimal change group), whereas 14 sinuses showed grade changes of ≥2 (substantial change group). Intergroup comparison showed that only the interval between the initial and final MRI scans differed significantly (p = 0.008). However, factors, such as age, sex, comorbidities, and history of dental procedures, did not differ significantly between the two groups.
This study shows the extent of change in fungus balls, primarily over time. These results offer critical insights into the natural course and progression of the maxillary sinus fungus ball.
4 Laryngoscope, 135:1315-1320, 2025.
鼻窦真菌球是鼻窦炎的一种常见形式，其发病率呈上升趋势。尽管对其治疗方法和致病因素已进行了充分研究，但真菌球不断演变的本质仍未阐明。本研究旨在调查和分析真菌球的变化模式。
本回顾性研究分析了从一家大型医疗中心的41497例接受脑部磁共振成像（MRI）检查的患者中选取的35例参与者的数据。根据MR图像将真菌球的范围从1到4进行分级，以评估其程度。基于人口统计学、MRI扫描间隔时间、合并症和特定的牙科干预措施，分析真菌球的变化过程。
真菌球分级随时间显示出显著进展。在对29个最初为低级别（0级、1级和2级）真菌球的鼻窦进行分析时，15个鼻窦的分级变化<2（无/最小变化组），而14个鼻窦的分级变化≥2（显著变化组）。组间比较显示，只有初始和最终MRI扫描之间的间隔时间存在显著差异（p = 0.008）。然而，两组之间的年龄、性别、合并症和牙科手术史等因素没有显著差异。
本研究显示了真菌球的变化程度，主要是随时间的变化。这些结果为上颌窦真菌球的自然病程和进展提供了关键见解。
4《喉镜》，135:1315 - 1320，2025年。
