Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, China.
The Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China.
Virulence. 2024 Dec;15(1):2424325. doi: 10.1080/21505594.2024.2424325. Epub 2024 Nov 8.
Well-intestinal health is crucial for better growth performance in pigs. Type 3 immunity, which is one of the three types of immune responses in mammals, plays a vital role in maintaining intestinal homoeostasis. Therefore, we initially introduce the type 3 immune cells in the intestine of pigs, including their distribution, development, and function. We then discuss the type 3 immune response under infection, encompassing bacterial, fungal, and viral infections. It also covers two major stresses in pigs: heat stress and weaning stress. Lastly, we discuss the effects of various nutrients and feed additives on the regulation of the type 3 immune response in pigs under infection. This review aims to contribute to the understanding of the interaction between infection and type 3 immunity in pigs and to illustrate how various nutrients modulate the type 3 immune response in pigs under diverse infections.
肠道健康对猪更好的生长性能至关重要。3 型免疫是哺乳动物三种免疫反应之一，在维持肠道内环境稳定方面发挥着重要作用。因此，我们首先介绍猪肠道中的 3 型免疫细胞，包括它们的分布、发育和功能。然后，我们讨论感染下的 3 型免疫反应，包括细菌、真菌和病毒感染。还包括猪的两种主要应激：热应激和断奶应激。最后，我们讨论了各种营养素和饲料添加剂在感染下对调节猪 3 型免疫反应的影响。本综述旨在促进对猪感染与 3 型免疫相互作用的理解，并说明在各种感染下，各种营养素如何调节猪的 3 型免疫反应。
