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婴儿孤立性心脏肌纤维瘤1例罕见病例

A Rare Case of Solitary Cardiac Myofibroma in an Infant.

作者信息

Yu Liwei, O'Leary Patrick W, Qureshi M Yasir, Maleszewski Joseph J, Stephens Elizabeth H, Dearani Joseph A, Ameduri Rebecca K

机构信息

Division of Pediatric Cardiology, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.

出版信息

World J Pediatr Congenit Heart Surg. 2025 Jan;16(1):137-140. doi: 10.1177/21501351241286453. Epub 2024 Nov 4.

Abstract

Solitary myofibromas are rare, benign, mesenchymal tumors typically found in the head and neck regions. We report an exceptionally rare case of a solitary cardiac myofibroma and its short-term management and outcome. A two-month-old infant was referred due to a murmur. Echocardiography revealed a 2 × 1 cm solitary mass originating from a mitral papillary muscle, causing severe regurgitation. Magnetic resonance imaging showed the mass to be homogeneous on T1, hyperintense on T2, and hypointense on first-pass perfusion imaging with no enhancement on delayed postcontrast imaging. The mass was surgically excised partially due to its involvement with the mitral valve. Postoperative recovery was uneventful, with echocardiography four months later showing no tumor recurrence and trivial mitral regurgitation. This report provides valuable imaging and pathology examples to aid in the recognition of this rare tumor and demonstrates that successful surgical excision is possible, even with significant cardiac involvement.

摘要

孤立性肌纤维瘤是一种罕见的良性间叶组织肿瘤,通常发生于头颈部。我们报告了一例极其罕见的孤立性心脏肌纤维瘤病例及其短期治疗情况和结果。一名两个月大的婴儿因心脏杂音前来就诊。超声心动图显示一个2×1厘米的孤立性肿块,起源于二尖瓣乳头肌,导致严重反流。磁共振成像显示该肿块在T1加权像上呈均匀信号,T2加权像上呈高信号,首次通过灌注成像上呈低信号,延迟增强成像上无强化。由于肿块累及二尖瓣,故行部分手术切除。术后恢复顺利,四个月后的超声心动图显示无肿瘤复发,二尖瓣反流轻微。本报告提供了有价值的影像学和病理学实例,有助于识别这种罕见肿瘤,并表明即使肿瘤严重累及心脏,成功的手术切除也是可行的。

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