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检查点抑制剂治疗:免疫相关不良事件管理。

Checkpoint inhibitor therapy: Immune-related adverse event management.

机构信息

Lori Davis and Mary Beth Casselbury are triage nurses, and Sharon Wilson is a clinical nurse leader at the Lipson Cancer Institute in Rochester, N.Y.

出版信息

Nursing. 2024 Nov 1;54(11):26-33. doi: 10.1097/NSG.0000000000000083. Epub 2024 Oct 18.

DOI:10.1097/NSG.0000000000000083
PMID:39497665
Abstract

Treatment with immune checkpoint inhibitors for cancer is associated with a high prevalence of multiple immune-related toxicities. Immune-related adverse events (irAEs) can occur anytime during treatment and up to 3 months after treatment. This article discusses checkpoint inhibitor therapy and describes the implementation of a patient education program focused on recognizing immunotherapy irAEs and their toxicities.

摘要

癌症的免疫检查点抑制剂治疗与多种免疫相关毒性的高患病率相关。免疫相关不良事件 (irAE) 可在治疗期间的任何时候以及治疗后 3 个月内发生。本文讨论了检查点抑制剂治疗,并描述了实施患者教育计划的情况,该计划侧重于识别免疫疗法 irAE 及其毒性。

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