Department of Otorhinolaryngology and Clinical Allergy Center, The First Affiliated Hospital, Nanjing Medical University, Nanjing, China.
Department of Rhinology, Eye and ENT Hospital, Fudan University, Shanghai, China.
J Infect Dev Ctries. 2024 Sep 30;18(9.1):S81-S91. doi: 10.3855/jidc.19234.
The World Health Organization declared an end to the global emergency status of COVID-19 in May of 2023. However, the impact of COVID-19 is far from over. Individuals who have recovered from COVID-19 continue to experience physiological, psychological, or cognitive symptoms, such as fatigue, shortness of breath, dizziness, and loss of smell or taste, known as long COVID. This review aims to describe the clinical characteristics of the upper respiratory tract infection (URTI) caused by SARS-CoV-2, and provide evidence for the prevention and treatment of SARS-CoV-2 infection by using nasal irrigation. COVID-19 and nasal irrigation: Nasal irrigation presents a promising adjunct to standard COVID-19 prevention and treatment protocols. This practice is theorized to diminish viral presence in the upper respiratory tract, a region identified as a primary site for SARS-CoV-2 replication and shedding. By facilitating the removal of viral particles and enhancing mucociliary clearance, nasal irrigation could potentially lessen the severity of URTI symptoms and slow transmission rates. The review consolidates current evidence of the efficacy and safety of this approach across various populations, underscoring its practicality in both preventive and therapeutic contexts.
We recommend that saline nasal irrigation is an effective, safe and convenient strategy to prevent the transmission of SARS-CoV-2 and alleviate the symptoms of URTI across various age groups.
世界卫生组织于 2023 年 5 月宣布结束 COVID-19 的全球紧急状态。然而，COVID-19 的影响远未结束。已经从 COVID-19 中康复的人继续经历生理、心理或认知症状，如疲劳、呼吸急促、头晕和嗅觉或味觉丧失，称为长 COVID。本综述旨在描述由 SARS-CoV-2 引起的上呼吸道感染 (URTI) 的临床特征，并通过使用鼻腔冲洗为 SARS-CoV-2 感染的预防和治疗提供证据。COVID-19 和鼻腔冲洗：鼻腔冲洗为标准的 COVID-19 预防和治疗方案提供了一种有前途的辅助方法。这种做法的理论依据是减少上呼吸道中病毒的存在，上呼吸道被认为是 SARS-CoV-2 复制和脱落的主要部位。通过促进病毒颗粒的清除和增强黏液纤毛清除功能，鼻腔冲洗可能会减轻 URTI 症状的严重程度并降低传播速度。该综述综合了目前针对各种人群的这种方法的疗效和安全性的证据，强调了它在预防和治疗方面的实用性。
我们建议盐水鼻腔冲洗是一种有效、安全且方便的策略，可以预防 SARS-CoV-2 的传播并缓解不同年龄段 URTI 的症状。
