Martinez Salas Alan de Jesus, Valero-Gomez Alfredo, Jimenez Garcia Aldo Daniel, Navarro-Ruesga Iñigo, Calvo-Mena Daniel, Zilli-Hernandez Stefan
Department of Urology, Hospital General Dra. Matilde Petra Montoya Lafragua, Mexico City, Mexico.
Department of Pathology, Hospital General Dra. Matilde Petra Montoya Lafragua, Mexico City, Mexico.
Urol Case Rep. 2024 Oct 16;57:102871. doi: 10.1016/j.eucr.2024.102871. eCollection 2024 Nov.
Prostate sarcoma is extremely rare, comprising less than 0.1 % of prostate cancers. A 61-year-old male presented to the emergency department with urinary retention and hematuria. Upon resolution of urinary retention, abdominal computed tomography showed a giant prostatic tumor, of approximately 1700 cubic centimeters, causing bilateral ureteric obstruction, and invasion of rectum and sigmoid colon. Laparotomy due to bowel obstruction showed peritoneal carcinomatosis. Palliative chemotherapy was initiated; however, he died due to hematological toxicity related to doxorubicin. Radical surgery is the ideal treatment; in cases of advanced or metastatic disease, adjuvant or palliative chemotherapy or radiotherapy withholds little or no benefit.