Bokhari Raghad A, Al-Zughbi Ali S, Bokhari Ziyad A
Pathology and Laboratory Medicine, King Fahad Medical City, Riyadh, SAU.
Pathology and Laboratory Medicine, King Saud Bin Abdulaziz University for Health Sciences College of Medicine, Riyadh, SAU.
Cureus. 2024 Nov 5;16(11):e73072. doi: 10.7759/cureus.73072. eCollection 2024 Nov.
-rearranged renal cell carcinoma (RCC) is a rare subtype of renal tumor that typically affects the pediatric age group. Previous exposure to chemotherapy agents increases the possibility of having this subtype. Morphologically, it displays a broad spectrum of growth patterns, but it can be distinguished by the presence of melanin pigment or psammoma bodies. Osseous metaplasia is an uncommon morphological finding in this particular subtype, and it has been reported in two cases in the literature. We describe the third case of -rearranged renal cell carcinoma with osseous metaplasia in a healthy 13-year-old male, presenting with worsening abdominal pain and hematuria.
重排性肾细胞癌(RCC)是一种罕见的肾肿瘤亚型,通常影响儿童年龄组。既往接触化疗药物会增加患此亚型的可能性。在形态学上,它表现出广泛的生长模式,但可通过黑色素沉着或砂粒体的存在来鉴别。骨化生在这种特殊亚型中是一种不常见的形态学表现,文献中已有两例报道。我们描述了第三例重排性肾细胞癌合并骨化生的病例,患者为一名13岁健康男性,表现为腹痛加重和血尿。