酵母中γ射线诱变的遗传分析。II. 诱变的等位基因特异性控制。
Genetic analysis of gamma-ray mutagenesis in yeast. II. Allele-specific control of mutagenesis.
作者信息
McKee R H, Lawrence C W
出版信息
Genetics. 1979 Oct;93(2):375-81. doi: 10.1093/genetics/93.2.375.
We find that partially different sets of gene functions are required for the production of different kinds of mutations induced by 60Co gamma rays in Saccharomyces cerevisiae. This observation is very similar to others made previously with respect to UV mutagenesis (LAWRENCE and CHRISTENSEN 1978a,b, 1979) and confirms the conclusion that such distinctive patterns of genetic control reflect properties of the test alleles and their genetic locations, rather than the kinds of lesions required to revert them. The data also support the model of mutagenic repair outlined in the first paper of this series (McKee and LAWRENCE 1979), in which partially different sets of gene functions are required for the production of different kinds of mutations, the formation of mutations at different genetic sites and the induction of mutations by different mutagens.
我们发现，在酿酒酵母中，产生由60Coγ射线诱导的不同类型突变需要部分不同的基因功能集。这一观察结果与之前关于紫外线诱变的其他观察结果非常相似（劳伦斯和克里斯蒂安森，1978a、b，1979），并证实了这样的结论：这种独特的遗传控制模式反映了测试等位基因的特性及其遗传位置，而不是使它们回复突变所需的损伤类型。这些数据也支持了本系列第一篇论文中概述的诱变修复模型（麦基和劳伦斯，1979），其中产生不同类型的突变、在不同遗传位点形成突变以及由不同诱变剂诱导突变需要部分不同的基因功能集。
Zotero 插件