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肾细胞癌中的静脉嗜性:一种罕见的影像学表现。

Venous Tropism in Renal Cell Carcinoma: A Rare Imaging Presentation.

作者信息

Rahman Nadeem Ur, Neeli Hemanth, Gupta Ayush, Sharma Jitendra, Minj Pratik

机构信息

Radiology, All India Institute of Medical Sciences, Bhopal, Bhopal, IND.

Pathology, All India Institute of Medical Sciences, Bhopal, Bhopal, IND.

出版信息

Cureus. 2024 Oct 6;16(10):e70927. doi: 10.7759/cureus.70927. eCollection 2024 Oct.

DOI:10.7759/cureus.70927
PMID:39502995
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11537773/
Abstract

Renal cell carcinoma (RCC) is one of the most prevalent malignancies in adults. Accurate staging and assessment of tumor extent are critical for effective management. RCC often demonstrates a tendency for venous invasion, commonly extending into the renal vein and inferior vena cava. However, RCC extending into the gonadal veins is an uncommon manifestation. In this report, we present the imaging features of a 62-year-old woman presented with left flank pain. The ultrasound examination revealed a large hyperechoic mass in the left renal fossa, replacing almost the entire left kidney with the contiguous extension of the tumor into the left renal vein and ovarian vein. Color Doppler showed the presence of flow within the thrombus, confirming the presence of a malignant thrombus. Contrast-enhanced CT examination revealed a large heterogeneously enhancing mass in the left kidney with the contiguous extension of tumor thrombus in the left renal vein, IVC, and into the left ovarian vein. This report highlights how imaging techniques can be instrumental in detecting and characterizing rare but significant tumor extensions, which can have crucial prognostic implications for overall patient management.

摘要

肾细胞癌(RCC)是成人中最常见的恶性肿瘤之一。准确分期和评估肿瘤范围对于有效治疗至关重要。RCC常表现出静脉侵犯倾向,通常延伸至肾静脉和下腔静脉。然而,RCC延伸至性腺静脉是一种罕见表现。在本报告中,我们呈现了一名62岁左侧腰痛女性的影像学特征。超声检查显示左肾窝有一个大的高回声肿块,几乎取代了整个左肾,肿瘤连续延伸至左肾静脉和卵巢静脉。彩色多普勒显示血栓内有血流,证实存在恶性血栓。增强CT检查显示左肾有一个大的不均匀强化肿块,肿瘤血栓连续延伸至左肾静脉、下腔静脉并进入左卵巢静脉。本报告强调了影像学技术在检测和表征罕见但重要的肿瘤延伸方面的作用,这对患者的整体治疗具有关键的预后意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b66/11537773/51409955d356/cureus-0016-00000070927-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b66/11537773/35b9ec633248/cureus-0016-00000070927-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b66/11537773/a036faa7a7f8/cureus-0016-00000070927-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b66/11537773/51409955d356/cureus-0016-00000070927-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b66/11537773/35b9ec633248/cureus-0016-00000070927-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b66/11537773/a036faa7a7f8/cureus-0016-00000070927-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b66/11537773/51409955d356/cureus-0016-00000070927-i03.jpg

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本文引用的文献

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Recent Advances in the Management of Clear Cell Renal Cell Carcinoma: Novel Biomarkers and Targeted Therapies.透明细胞肾细胞癌治疗的最新进展:新型生物标志物与靶向治疗
Cancers (Basel). 2023 Jun 16;15(12):3207. doi: 10.3390/cancers15123207.
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Characterizing Tumor Thrombus Arising from Non-Clear Cell Renal Cell Carcinoma.非透明细胞肾细胞癌来源肿瘤血栓的特征分析
Eur Urol Open Sci. 2022 Jul 25;43:28-34. doi: 10.1016/j.euros.2022.07.001. eCollection 2022 Sep.
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Clinical Characteristics and Management of Ovarian Vein Thrombosis: A Case Series.
卵巢静脉血栓形成的临床特征与管理:病例系列
Front Cardiovasc Med. 2022 Jun 16;9:916920. doi: 10.3389/fcvm.2022.916920. eCollection 2022.
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Renal Cell Carcinoma with Direct Extension into the Gonadal Vein, Uterus, Fallopian Tube, and Bilateral Ovaries: A Case Report.肾细胞癌直接侵犯性腺静脉、子宫、输卵管及双侧卵巢:一例报告
J Kidney Cancer VHL. 2020 Aug 14;7(3):1-4. doi: 10.15586/jkcvhl.2020.130. eCollection 2020.
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Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up†.肾细胞癌:ESMO 诊断、治疗及随访临床实践指南†
Ann Oncol. 2019 May 1;30(5):706-720. doi: 10.1093/annonc/mdz056.
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Tumor thrombus: incidence, imaging, prognosis and treatment.肿瘤血栓:发病率、影像学、预后及治疗
Cardiovasc Diagn Ther. 2017 Dec;7(Suppl 3):S165-S177. doi: 10.21037/cdt.2017.09.16.
7
Review of renal cell carcinoma and its common subtypes in radiology.肾细胞癌及其常见亚型的放射学综述。
World J Radiol. 2016 May 28;8(5):484-500. doi: 10.4329/wjr.v8.i5.484.
8
Gonadal vein tumor thrombosis due to renal cell carcinoma.肾细胞癌导致的性腺静脉肿瘤血栓形成。
Indian J Urol. 2015 Jan-Mar;31(1):79-80. doi: 10.4103/0970-1591.139553.
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