Olszewska Aneta, Forszt Dominika, Szymczak Aleksandra, Górna Natalie, Gedrange Tomasz, Czajka-Jakubowska Agata, Matys Jacek
Department of Orthodontics and Temporomandibular Disorders, Poznan University of Medical Sciences, Poland.
Department of Risk Group Dentistry, Poznan University of Medical Sciences, Poland.
Adv Clin Exp Med. 2025 Jun;34(6):987-1010. doi: 10.17219/acem/190202.
Dental anesthesia administration often triggers unpleasant sensations, particularly needle injection-related pain, which can evoke fear among patients, especially in the pediatric population. Vibration and low-level laser therapy (LLLT) have been extensively studied as potential methods for alleviating pain. Additionally, phentolamine mesylate (PM) has shown promise in reducing the duration of anesthesia. From a clinical perspective, inadequate control over the persistence of the anesthetic effect may lead to complications associated with its prolonged duration, such as self-injuries or functional impairments.
This review aimed to systematically summarize and compare methods of alleviating pain during local anesthesia and reducing its duration.
In November 2023, an electronic search was systematically conducted across PubMed, Web of Science, and Scopus databases using keywords (pain) AND (anesthesia) AND ((phentolamine) or (vibration) or (LLLT) OR (PBM)). The initial pool consisted of 495 records, from which 241 duplicates were eliminated. After careful examination of the remaining articles, 40 were included. The study adhered to the PRISMA guidelines.
Most studies reported beneficial effects of LLLT and vibration; however, some did not corroborate these findings. Four studies had inconclusive results. Regarding anesthesia duration involving PM and LLLT, the majority of studies exhibited notable reductions, although no significant differences were revealed in 1 study.
Vibration and LLLT appear to be advantageous methods in alleviating pain associated with local anesthesia administration. Phentolamine mesylate and LLLT are efficient in reversing local anesthesia.
牙科麻醉给药常常引发不适感觉，尤其是与针头注射相关的疼痛，这可能会引起患者恐惧，在儿科患者中尤为明显。振动和低强度激光疗法（LLLT）作为缓解疼痛的潜在方法已得到广泛研究。此外，甲磺酸酚妥拉明（PM）在缩短麻醉持续时间方面已显示出前景。从临床角度来看，对麻醉效果持续时间控制不当可能会导致与其持续时间延长相关的并发症，如自我伤害或功能障碍。
本综述旨在系统总结和比较局部麻醉期间缓解疼痛及其持续时间的方法。
2023年11月，使用关键词（疼痛）AND（麻醉）AND（（酚妥拉明）或（振动）或（LLLT）或（PBM））在PubMed、科学网和Scopus数据库中进行了系统的电子检索。初始文献库包含495条记录，其中241条重复记录被剔除。在仔细审查其余文章后，纳入了40篇。该研究遵循PRISMA指南。
大多数研究报告了LLLT和振动的有益效果；然而，一些研究并未证实这些发现。四项研究结果不明确。关于涉及PM和LLLT的麻醉持续时间，大多数研究显示出显著缩短，尽管有一项研究未发现显著差异。
振动和LLLT似乎是缓解局部麻醉给药相关疼痛的有利方法。甲磺酸酚妥拉明和LLLT在逆转局部麻醉方面是有效的。
