Renaud Solène, Freire Mila, O'Toole Elizabeth, Huneault Louis, Llido Marie, Ringwood Brendon, Juette Tristan, Gagnon Dominique
Faculty of Veterinary Medicine, University of Montreal, Saint-Hyacinthe, Québec, Canada.
Centre Vétérinaire Rive-Sud, Brossard, Québec, Canada.
Vet Surg. 2025 Feb;54(2):276-286. doi: 10.1111/vsu.14189. Epub 2024 Nov 6.
To report demographics, clinical signs, physical examination, diagnostic test results, surgical findings, and prognostic factors for in-hospital postoperative mortality following biliary peritonitis surgery in dogs.
Retrospective, multi-institutional cohort study.
Thirty-three client-owned dogs.
The medical records of dogs that underwent surgery for biliary peritonitis between 2015 and 2021 were reviewed. Dogs were included if they had a definitive diagnosis of biliary peritonitis and a surgery report. Information on demographics, clinical signs and duration, physical examination findings, laboratory and diagnostic imaging results, surgery, perioperative medical treatment, and complications for each patient was obtained. Statistical analyses were performed to identify risk factors that affected survival.
Cholecystectomy was the procedure most frequently performed (31/33, 94%). The overall mortality rate was 36% (12/33). Survival was affected negatively by hyperbilirubinemia (p = .049), administration of vasopressors (p = .002), renal dysfunction (p = .008), and number of postoperative complications (p = .005). A mortality rate of 50% was observed in dogs with a total bilirubin level greater than 60.5 μmol/L. There was no difference in mortality rate between septic and nonseptic biliary effusions.
New prognostic factors associated with in-hospital postoperative mortality in dogs treated surgically for biliary peritonitis were identified, while others that had been reported previously were confirmed. A preoperative bilirubin threshold value associated with a 50% mortality was identified.
Additional information that could help to predict survival in dogs with biliary peritonitis has been provided. However, further research is warranted.
报告犬胆汁性腹膜炎手术后院内术后死亡率的人口统计学、临床症状、体格检查、诊断测试结果、手术发现及预后因素。
回顾性多机构队列研究。
33只客户拥有的犬。
回顾2015年至2021年间接受胆汁性腹膜炎手术的犬的病历。确诊为胆汁性腹膜炎且有手术报告的犬被纳入研究。获取每只患者的人口统计学、临床症状及持续时间、体格检查结果、实验室和诊断影像学结果、手术、围手术期药物治疗及并发症等信息。进行统计分析以确定影响生存的危险因素。
胆囊切除术是最常施行的手术（31/33，94%）。总死亡率为36%（12/33）。高胆红素血症（p = 0.049）、使用血管加压药（p = 0.002）、肾功能不全（p = 0.008）及术后并发症数量（p = 0.005）对生存有负面影响。总胆红素水平大于60.5 μmol/L的犬死亡率为50%。感染性和非感染性胆汁积液的死亡率无差异。
确定了与手术治疗犬胆汁性腹膜炎院内术后死亡率相关的新预后因素，同时证实了先前报道的其他因素。确定了与50%死亡率相关的术前胆红素阈值。
提供了有助于预测犬胆汁性腹膜炎生存情况的更多信息。然而，仍需进一步研究。
