• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Syndecans in Alzheimer's disease: pathogenetic mechanisms and potential therapeutic targets.

作者信息

Balistreri Carmela Rita, Monastero Roberto

机构信息

Cellular, Molecular and Clinical Pathological Laboratory, Department of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), University of Palermo, Palermo, Italy (Balistreri CR).

Memory and Parkinson's disease Center, Policlinico "Paolo Giaccone", Palermo; Department of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), University of Palermo, Via La Loggia 1, Palermo, Italy (Monastero R).

出版信息

Neural Regen Res. 2025 Sep 1;20(9):2594-2595. doi: 10.4103/NRR.NRR-D-24-00659. Epub 2024 Sep 24.

DOI:10.4103/NRR.NRR-D-24-00659
PMID:39503428
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11801285/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27e2/11801285/d1527d2d4d05/NRR-20-2594-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27e2/11801285/d1527d2d4d05/NRR-20-2594-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27e2/11801285/d1527d2d4d05/NRR-20-2594-g001.jpg

相似文献

1
Syndecans in Alzheimer's disease: pathogenetic mechanisms and potential therapeutic targets.阿尔茨海默病中的 Syndecans：发病机制及潜在治疗靶点
Neural Regen Res. 2025 Sep 1;20(9):2594-2595. doi: 10.4103/NRR.NRR-D-24-00659. Epub 2024 Sep 24.
2
Role of Syndecans in Lipid Metabolism and Human Diseases.Syndecans在脂质代谢及人类疾病中的作用
Adv Exp Med Biol. 2015;855:241-58. doi: 10.1007/978-3-319-17344-3_10.
3
Contribution of syndecans to cellular internalization and fibrillation of amyloid-β(1-42).黏附素对淀粉样β(1-42)细胞内化和纤维形成的贡献。
Sci Rep. 2019 Feb 4;9(1):1393. doi: 10.1038/s41598-018-37476-9.
4
Neuroinflammation as a mechanism linking hypertension with the increased risk of Alzheimer's disease.神经炎症作为一种将高血压与阿尔茨海默病风险增加相联系的机制。
Neural Regen Res. 2022 Nov;17(11):2342-2346. doi: 10.4103/1673-5374.336869.
5
Syndecans and Pancreatic Ductal Adenocarcinoma.黏附素和胰腺导管腺癌。
Biomolecules. 2021 Feb 25;11(3):349. doi: 10.3390/biom11030349.
6
Heparan sulfate proteoglycan expression in cerebrovascular amyloid beta deposits in Alzheimer's disease and hereditary cerebral hemorrhage with amyloidosis (Dutch) brains.硫酸乙酰肝素蛋白聚糖在阿尔茨海默病和遗传性脑出血伴淀粉样变性（荷兰型）脑的脑血管淀粉样β沉积物中的表达。
Acta Neuropathol. 2001 Dec;102(6):604-14. doi: 10.1007/s004010100414.
7
Syndecan-3 as a Novel Biomarker in Alzheimer's Disease.Syndecan-3 作为阿尔茨海默病的新型生物标志物。
Int J Mol Sci. 2022 Mar 21;23(6):3407. doi: 10.3390/ijms23063407.
8
Integration of network pharmacology and molecular docking to explore the molecular mechanism of Cordycepin in the treatment of Alzheimer's disease.整合网络药理学与分子对接以探究虫草素治疗阿尔茨海默病的分子机制。
Front Aging Neurosci. 2022 Dec 23;14:1058780. doi: 10.3389/fnagi.2022.1058780. eCollection 2022.
9
Syndecans in angiogenesis and endothelial cell biology.多配体蛋白聚糖在血管生成和内皮细胞生物学中的作用
Biochem Soc Trans. 2014 Dec;42(6):1643-6. doi: 10.1042/BST20140232.
10
Computational Analysis of Pathogenetic Pathways in Alzheimer's Disease and Prediction of Potential Therapeutic Drugs.阿尔茨海默病致病途径的计算分析及潜在治疗药物预测
Brain Sci. 2022 Jun 24;12(7):827. doi: 10.3390/brainsci12070827.

引用本文的文献

1
Shed Syndecans (1-3), ELA-32, BDNF, NLR, and hs-CRP in Parkinson's Disease: Appropriate Diagnostic and Prognostic Biomarkers When Combined in a Unique Panel.帕金森病中的脱落 Syndecans（1 - 3）、ELA - 32、脑源性神经营养因子、中性粒细胞与淋巴细胞比值及高敏 C 反应蛋白：联合纳入独特检测组时作为合适的诊断和预后生物标志物
Int J Mol Sci. 2025 May 8;26(10):4503. doi: 10.3390/ijms26104503.
2
Local and Systemic Endothelial Damage in Patients with CEAP C2 Chronic Venous Insufficiency: Role of Mesoglycan.CEAP C2 级慢性静脉功能不全患者的局部和全身内皮损伤：硫酸软骨素的作用
Int J Mol Sci. 2025 Apr 24;26(9):4046. doi: 10.3390/ijms26094046.

本文引用的文献

1
Focus of endothelial glycocalyx dysfunction in ischemic stroke and Alzheimer's disease: Possible intervention strategies.关注缺血性脑卒中与阿尔茨海默病中内皮糖萼功能障碍：可能的干预策略。
Ageing Res Rev. 2024 Aug;99:102362. doi: 10.1016/j.arr.2024.102362. Epub 2024 Jun 1.
2
Neuroinflammation and Neurodegenerative Diseases: How Much Do We Still Not Know?神经炎症与神经退行性疾病：我们仍有多少未知？
Brain Sci. 2023 Dec 23;14(1):19. doi: 10.3390/brainsci14010019.
3
Therapeutic strategies targeting the endothelial glycocalyx.靶向内皮糖萼的治疗策略。
Curr Opin Clin Nutr Metab Care. 2023 Nov 1;26(6):543-550. doi: 10.1097/MCO.0000000000000973. Epub 2023 Aug 9.
4
Sex and gender differences in Alzheimer's disease, Parkinson's disease, and Amyotrophic Lateral Sclerosis: A narrative review.阿尔茨海默病、帕金森病和肌萎缩侧索硬化症中的性别差异：叙事性综述。
Mech Ageing Dev. 2023 Jun;212:111821. doi: 10.1016/j.mad.2023.111821. Epub 2023 Apr 29.
5
Promising Strategies for Preserving Adult Endothelium Health and Reversing Its Dysfunction: From Liquid Biopsy to New Omics Technologies and Noninvasive Circulating Biomarkers.有前景的维持成人内皮健康和逆转其功能障碍的策略：从液体活检到新的组学技术和非侵入性循环生物标志物。
Int J Mol Sci. 2022 Jul 7;23(14):7548. doi: 10.3390/ijms23147548.
6
Syndecan-3 as a Novel Biomarker in Alzheimer's Disease.Syndecan-3 作为阿尔茨海默病的新型生物标志物。
Int J Mol Sci. 2022 Mar 21;23(6):3407. doi: 10.3390/ijms23063407.
7
Vascular ageing and the related complications in the brain: New insights on related mechanisms and their translational applications.血管衰老与脑部相关并发症：相关机制及其转化应用的新见解
Mech Ageing Dev. 2021 Jun;196:111469. doi: 10.1016/j.mad.2021.111469. Epub 2021 Mar 15.
8
Heparan sulfate proteoglycans as possible diagnostic molecular tools with therapeutic potential in Alzheimer´s disease.硫酸乙酰肝素蛋白聚糖作为阿尔茨海默病中具有治疗潜力的可能诊断分子工具。
Neural Regen Res. 2021 Jul;16(7):1404-1405. doi: 10.4103/1673-5374.301056.
9
Heparan Sulfate Proteoglycans Undergo Differential Expression Alterations in Alzheimer Disease Brains.硫酸乙酰肝素蛋白聚糖在阿尔茨海默病大脑中发生差异表达改变。
J Neuropathol Exp Neurol. 2020 May 1;79(5):474-483. doi: 10.1093/jnen/nlaa016.
10
Developmental programming of adult haematopoiesis system.成人造血系统的发育编程。
Ageing Res Rev. 2019 Sep;54:100918. doi: 10.1016/j.arr.2019.100918. Epub 2019 Jun 19.