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缓症埃格特菌致菌血症的临床和微生物学特征。

Clinical and microbiological characteristics of Eggerthella lenta causing bacteremia.

机构信息

Sierrallana Hospital, Microbiology Service, Cantabria, Spain.

Basurto University Hospital, Clinical Microbiology Service, Bilbao, Basque Country, Spain; Biocruces Bizkaia Health Research Institute, Barakaldo, Basque Country, Spain.

出版信息

Enferm Infecc Microbiol Clin (Engl Ed). 2024 Nov;42(9):512-515. doi: 10.1016/j.eimce.2024.05.014.

DOI:10.1016/j.eimce.2024.05.014
PMID:39505460
Abstract

Eggerthella lenta is an obligate anaerobic, Gram-positive bacilli, belonging to the human microbiota of gastrointestinal and female reproductive tracts, oral cavity and prostate gland. In this article, we aim to describe clinical and microbiological characteristics of seven E. lenta strains causing bacteremia. We conducted a descriptive retrospective study including all E. lenta strains causing bacteremia, from February 2019 to August 2023 at the Basurto University Hospital. Seven patients were included in the study with a mean age of 72.7 years. Six patients presented risk factors associated with bacterial infections. All patients were admitted to the hospital because of suspicious of bloodstream infection associated with abdominal symptoms for intravenous antibiotic treatment. Four E. lenta isolates were resistant to penicillin, while all isolates presented high MICs to piperacillin/tazobactam and low MICs to amoxicillin/clavulanic acid. All patients recovered without no complications.

摘要

迟缓埃格特菌是一种专性厌氧、革兰阳性杆菌,属于胃肠道和女性生殖道、口腔和前列腺的人体微生物群。在本文中,我们旨在描述 7 株引起菌血症的迟缓埃格特菌的临床和微生物学特征。我们进行了一项描述性回顾性研究,包括 2019 年 2 月至 2023 年 8 月在巴斯克大学医院引起菌血症的所有迟缓埃格特菌菌株。该研究纳入 7 例患者,平均年龄为 72.7 岁。6 例患者存在与细菌感染相关的危险因素。所有患者因疑似与腹部症状相关的血流感染而入院,接受静脉抗生素治疗。4 株迟缓埃格特菌分离株对青霉素耐药,而所有分离株对哌拉西林/他唑巴坦的 MIC 值较高,对阿莫西林/克拉维酸的 MIC 值较低。所有患者均未出现并发症而康复。

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