Sano A, Kotani K, Kakimoto Y
J Neurochem. 1986 Apr;46(4):1046-9. doi: 10.1111/j.1471-4159.1986.tb00616.x.
A new dipeptide, alpha-(gamma-aminobutyryl)-hypusine, was identified in bovine brain. This compound was isolated from trichloroacetic acid-soluble fraction of bovine brain with five steps of ion-exchange chromatography. Its structure was postulated by routine chemical analyses and determined by synthesis. The amount of the compound isolated from 1.2 kg of bovine brain was 870 nmol.
在牛脑中鉴定出一种新的二肽,α-(γ-氨基丁酰基)-hypusine。该化合物是从牛脑的三氯乙酸可溶部分通过五步离子交换色谱法分离得到的。其结构通过常规化学分析推测,并通过合成确定。从1.2千克牛脑中分离出的该化合物的量为870纳摩尔。