独立于肺毛细血管楔压的血流动力学标志物能够区分毛细血管前和毛细血管后运动诱发的肺动脉高压。
Hemodynamic markers independent of pulmonary capillary wedge pressure can discriminate between pre and postcapillary exercise-induced pulmonary hypertension.
作者信息
Montovano Margaret, Scheel Paul J, Cubero Salazar Ilton M, Hassoun Paul M, Tedford Ryan J, Hsu Steven
机构信息
Division of Cardiology, Department of Medicine The Johns Hopkins University School of Medicine Baltimore Maryland USA.
Division of Pulmonary and Critical Care Medicine, Department of Medicine The Johns Hopkins University School of Medicine Baltimore Maryland USA.
出版信息
Pulm Circ. 2024 Nov 6;14(4):e70002. doi: 10.1002/pul2.70002. eCollection 2024 Oct.
The discrimination between pre and postcapillary exercise-induced pulmonary hypertension relies on accurate measurement of pulmonary capillary wedge pressure, which can be unreliable. We found that exercise pulmonary artery compliance and right atrial pressure (AUC 0.88, 0.89, respectively) can differentiate subtypes of exercise-induced pulmonary hypertension in the absence of wedge pressure.
毛细血管前和毛细血管后运动诱发的肺动脉高压之间的鉴别依赖于肺毛细血管楔压的准确测量，而这可能并不可靠。我们发现，在没有楔压的情况下，运动肺动脉顺应性和右心房压力（曲线下面积分别为0.88、0.89）可以区分运动诱发的肺动脉高压的亚型。
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