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大麻及其对乳房缩小手术结果和生活质量的影响:一项匹配分析。

Marijuana and Its Implications in Breast Reduction Surgery Outcomes and Quality of Life: A Matched Analysis.

作者信息

Ewing Jane N, Amro Chris, Chang Ashley, Gala Zachary, Lemdani Mehdi S, Broach Robyn B, Fischer John P, Serletti Joseph M, Azoury Saïd C

机构信息

From the Division of Plastic Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, Pa.

Hansjörg Wyss Department of Plastic Surgery, NYU Langone, New York, N.Y.

出版信息

Plast Reconstr Surg Glob Open. 2024 Nov 5;12(11):e6273. doi: 10.1097/GOX.0000000000006273. eCollection 2024 Nov.

Abstract

BACKGROUND

With marijuana use on the rise, its influence on surgical outcomes, particularly for breast reduction, warrants investigation. This study aims to clarify marijuana's effects on breast reduction surgery outcomes, given its limited research focus despite potential perioperative implications.

METHODS

A retrospective review was conducted from 2016 to 2022 of patients with/without marijuana use undergoing breast reduction. Propensity score-matching considered age, body mass index, ptosis, and breast tissue mass. Patient demographics, clinical attributes, and postoperative details were analyzed. Quality-of-life (QoL) changes were gauged using pre- and postoperative BREAST-Q.

RESULTS

Of 415 patients who underwent breast reduction, 140 patients documented marijuana use. After propensity matching, a total of 108 patients (54 marijuana users versus 54 nonusers) were analyzed. The average age was 39 years ± 12 and body mass index 30.1 kg/m ± 5.3. There were no differences between the 2 groups in comorbidities, breast symmetry, excision patterns, pedicle use, or drain count ( > 0.05). Furthermore, surgical outcomes including surgical site occurrences, scarring, pain levels, hypersensitivity, or sensation loss were comparable between the groups ( > 0.05). There were also no differences in number of readmissions, reoperations, or emergency department visits ( > 0.05). Both groups showed enhanced postoperative QoL, regardless of marijuana usage.

CONCLUSIONS

This study indicates that marijuana use does not significantly impact breast reduction surgery outcomes. Comparable surgical results and postoperative QoL improvements were observed in both marijuana users and nonusers. This study provides surgeons with the knowledge to offer more informed patient counseling regarding the implications of marijuana use in relation to breast reduction procedures.

摘要

背景

随着大麻使用的增加,其对外科手术结果的影响,尤其是对乳房缩小手术的影响,值得研究。鉴于尽管大麻在围手术期可能有影响,但相关研究重点有限,本研究旨在阐明大麻对乳房缩小手术结果的影响。

方法

对2016年至2022年接受或未接受大麻使用的乳房缩小手术患者进行回顾性研究。倾向评分匹配考虑了年龄、体重指数、上睑下垂和乳腺组织量。分析了患者的人口统计学、临床特征和术后细节。使用术前和术后的BREAST-Q量表评估生活质量(QoL)的变化。

结果

在415例行乳房缩小手术的患者中,有140例记录了大麻使用情况。经过倾向匹配后,共分析了108例患者(54例大麻使用者和54例非使用者)。平均年龄为39岁±12岁,体重指数为30.1kg/m²±5.3。两组在合并症、乳房对称性、切除方式、蒂的使用或引流管数量方面无差异(P>0.05)。此外,两组在手术部位并发症、瘢痕形成、疼痛程度、超敏反应或感觉丧失等手术结果方面相当(P>0.05)。再次入院、再次手术或急诊就诊的次数也无差异(P>0.05)。无论是否使用大麻,两组术后的生活质量均有所提高。

结论

本研究表明,大麻使用对乳房缩小手术结果无显著影响。大麻使用者和非使用者的手术结果相当,术后生活质量均有所改善。本研究为外科医生提供了相关知识,以便在乳房缩小手术中就大麻使用的影响为患者提供更明智的咨询。

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