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颅内结核瘤与CT扫描

Intracranial tuberculoma and the CT scan.

作者信息

Vengsarkar U S, Pisipaty R P, Parekh B, Panchal V G, Shetty M N

出版信息

J Neurosurg. 1986 Apr;64(4):568-74. doi: 10.3171/jns.1986.64.4.0568.

Abstract

Computerized tomography (CT) has greatly influenced the diagnosis and management of intracranial tuberculomas and has helped us to formulate guidelines for the management of these lesions. Solid and ring-enhancing lesions seen on CT scans are diagnostic of tuberculoma if supported by other clinical and ancillary criteria. Conservative management of intracranial tuberculoma is usually indicated because serial CT scans have shown complete disappearance of these lesions with antituberculous therapy. Only lesions associated with raised intracranial pressure and CT evidence of a mass effect should be considered for surgery. Nonresponse to antituberculous therapy, as judged by serial CT scanning, should raise doubts regarding the diagnosis of a tuberculomatous lesion, and therefore such lesions should be subjected to surgery and histopathological confirmation. Representative clinical cases illustrating the principles of diagnosis and management of intracranial tuberculoma with the help of CT scanning are briefly described and discussed.

摘要

计算机断层扫描(CT)对颅内结核瘤的诊断和治疗产生了重大影响,并帮助我们制定了这些病变的治疗指南。如果CT扫描上看到的实性和环形强化病变得到其他临床及辅助标准的支持,则可诊断为结核瘤。颅内结核瘤通常采用保守治疗,因为系列CT扫描显示,经抗结核治疗后这些病变会完全消失。只有与颅内压升高及有占位效应的CT证据相关的病变才应考虑手术。根据系列CT扫描判断,对抗结核治疗无反应应引起对结核瘤性病变诊断的怀疑,因此此类病变应接受手术及组织病理学确诊。本文简要描述并讨论了借助CT扫描说明颅内结核瘤诊断和治疗原则的代表性临床病例。

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