Zhang Lijuan, Wen Kun, Wang Yan, Yang Lihong, Sun Minghong, Tao Yi
Ⅰ （ 400000） Phase Ⅰ Clinical Trial Ward, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400000, China.
Sichuan Da Xue Xue Bao Yi Xue Ban. 2024 Sep 20;55(5):1226-1231. doi: 10.12182/20240960506.
To explore the mediating effect of fatigue between social support and depression in hospitalized patients with ischemic stroke, so as to provide reference for improving post-stroke depression.
A total of 142 hospitalized patients with ischemic stroke were enrolled and investigation was conducted with self-rating depression scale (SDS), social support rating scale (SSRS), and fatigue severity scale (FSS). Spearman's correlation analysis was used to analyze the correlation between the variables. A model for the mediating effect between the variables was established by using the AMOS 23.0 software to analyze the mediating effect of fatigue between social support and depression. The Bootstrap method was used to test the significance of intermediary effect.
The scores for SDS, SSRS, and FSS in the hospitalized ischemic stroke patients enrolled were 48.96±9.09, 31.34±8.35, and 30.70±13.99, respectively. Spearman's correlation analysis showed that depression was positively correlated with fatigue and negatively correlated with social support. In addition, fatigue was negatively correlated with social support. Analysis of the mediating effect model established that fatigue played a mediating role between social support and depression in patients with ischemic stroke, with the mediating effect value being -0.170 and the mediating effect accounting for 90.0% of the total effect.
The effect of social support on depression in hospitalized patients with ischemic stroke is mainly achieved by affecting the sense of fatigue. Health workers should pay attention to the severity of fatigue of patients and reduce their sense of fatigue as much as possible, which will help enhance social support for the patients and reduce their depression.
探讨疲劳在缺血性脑卒中住院患者社会支持与抑郁之间的中介作用，为改善脑卒中后抑郁提供参考。
选取142例缺血性脑卒中住院患者，采用自评抑郁量表（SDS）、社会支持评定量表（SSRS）及疲劳严重程度量表（FSS）进行调查。采用Spearman相关分析对各变量之间的相关性进行分析。运用AMOS 23.0软件建立变量间的中介效应模型，分析疲劳在社会支持与抑郁之间的中介作用。采用Bootstrap法检验中介效应的显著性。
纳入的缺血性脑卒中住院患者SDS、SSRS、FSS得分分别为48.96±9.09、31.34±8.35、30.70±13.99。Spearman相关分析显示，抑郁与疲劳呈正相关，与社会支持呈负相关。此外，疲劳与社会支持呈负相关。中介效应模型分析显示，疲劳在缺血性脑卒中患者社会支持与抑郁之间起中介作用，中介效应值为-0.170，中介效应占总效应的90.0%。
社会支持对缺血性脑卒中住院患者抑郁的影响主要通过影响疲劳感来实现。医护人员应关注患者的疲劳严重程度，尽可能减轻其疲劳感，这将有助于增强对患者的社会支持，减轻其抑郁情绪。
