局部应用氨甲环酸治疗鼻出血有效吗？
Is Topical Tranexamic Acid Effective in Treating Epistaxis?
作者信息
Munroe Kelti M, Sowerby Leigh J, Chin Christopher J
机构信息
Division of Otolaryngology - Head and Neck Surgery, Dalhousie University, Halifax, Nova Scotia, Canada.
Department of Otolaryngology - Head and Neck Surgery, Western University, London, Ontario, Canada.
出版信息
Laryngoscope. 2025 Feb;135(2):488-490. doi: 10.1002/lary.31900. Epub 2024 Nov 7.
Abstract
Topical tranexamic acid is used to treat epistaxis. We reviewed the evidence for this practice, and found based on the current literature, it may be a useful adjunct in managing epistaxis.
摘要
局部用氨甲环酸用于治疗鼻出血。我们回顾了这一疗法的证据，并根据当前文献发现，它可能是鼻出血治疗中的一种有用辅助手段。
相似文献
1
Is Topical Tranexamic Acid Effective in Treating Epistaxis?局部应用氨甲环酸治疗鼻出血有效吗？
Laryngoscope. 2025 Feb;135(2):488-490. doi: 10.1002/lary.31900. Epub 2024 Nov 7.
2
Topical tranexamic acid (TXA) for the management of a bleeding arteriovenous fistula.局部使用氨甲环酸（TXA）治疗出血性动静脉瘘。
Am J Emerg Med. 2020 Feb;38(2):407.e5-407.e6. doi: 10.1016/j.ajem.2019.158441. Epub 2019 Sep 11.
3
Topical tranexamic acid for spontaneous epistaxis.外用氨甲环酸治疗自发性鼻出血。
Medwave. 2018 Dec 10;18(8):e7372. doi: 10.5867/medwave.2018.08.7371.
4
Tranexamic acid for patients with nasal haemorrhage (epistaxis).氨甲环酸用于鼻出血患者。
Cochrane Database Syst Rev. 2018 Dec 31;12(12):CD004328. doi: 10.1002/14651858.CD004328.pub3.
5
Is topical tranexamic acid a better alternative for selected cases of anterior epistaxis management in the ED?局部使用氨甲环酸是否是急诊科某些前鼻出血病例治疗的更好选择？
Am J Emerg Med. 2018 Apr;36(4):734.e1-734.e2. doi: 10.1016/j.ajem.2018.01.020. Epub 2018 Jan 4.
6
Best evidence topic reports. BET 3: Topical intranasal tranexamic acid for spontaneous epistaxis.最佳证据主题报告。BET 3：局部鼻腔内使用氨甲环酸治疗自发性鼻出血。
Emerg Med J. 2014 May;31(5):436-7. doi: 10.1136/emermed-2014-203763.3.
7
Role of topical tranexamic acid in the management of idiopathic anterior epistaxis in adult patients in the emergency department.局部应用氨甲环酸在急诊科成年患者特发性鼻出血管理中的作用
Am J Health Syst Pharm. 2016 Nov 1;73(21):1755-1759. doi: 10.2146/ajhp150829.
8
BET 1: Intravenous tranexamic acid in the treatment of acute epistaxis.BET 1：静脉注射氨甲环酸治疗急性鼻出血。
Emerg Med J. 2015 Dec;32(12):969-70. doi: 10.1136/emermed-2015-204985.1.
9
Novel use of tranexamic acid to reduce the need for Nasal Packing in Epistaxis (NoPac) randomised controlled trial: research protocol.氨甲环酸在减少鼻出血中鼻腔填塞需求（NoPac）的新用途：随机对照试验研究方案。
BMJ Open. 2019 Feb 15;9(2):e026882. doi: 10.1136/bmjopen-2018-026882.
10
Does Oral or Topical Tranexamic Acid Control Bleeding From Epistaxis?口服或外用氨甲环酸能否控制鼻出血？
Ann Emerg Med. 2019 Aug;74(2):300-302. doi: 10.1016/j.annemergmed.2019.01.042. Epub 2019 May 3.
本文引用的文献
1
Intranasal Topical Application of Tranexamic Acid in Atraumatic Anterior Epistaxis: A Double-Blind Randomized Clinical Trial.鼻腔内局部应用氨甲环酸治疗非创伤性前鼻出血：一项双盲随机临床试验。
Ann Emerg Med. 2022 Sep;80(3):182-188. doi: 10.1016/j.annemergmed.2022.04.010. Epub 2022 Jun 23.
2
Efficacy of topical tranexamic acid in epistaxis: A systematic review and meta-analysis.局部使用氨甲环酸治疗鼻出血的疗效：系统评价和荟萃分析。
Am J Emerg Med. 2022 Jan;51:169-175. doi: 10.1016/j.ajem.2021.10.043. Epub 2021 Nov 1.
3
The Use of Tranexamic Acid to Reduce the Need for Nasal Packing in Epistaxis (NoPAC): Randomized Controlled Trial.氨甲环酸减少鼻出血填塞需求（NoPAC）的使用：随机对照试验。
Ann Emerg Med. 2021 Jun;77(6):631-640. doi: 10.1016/j.annemergmed.2020.12.013. Epub 2021 Feb 19.
4
Topical Tranexamic Acid versus Phenylephrine-lidocaine for the Treatment of Anterior Epistaxis in Patients Taking Aspirin or Clopidogrel; a Randomized Clinical Trial.局部用氨甲环酸与去氧肾上腺素-利多卡因治疗服用阿司匹林或氯吡格雷患者的前位鼻出血：一项随机临床试验
Arch Acad Emerg Med. 2020 Nov 19;9(1):e6. doi: 10.22037/aaem.v9i1.875. eCollection 2021.
5
Evaluating Effectiveness of Nasal Compression With Tranexamic Acid Compared With Simple Nasal Compression and Merocel Packing: A Randomized Controlled Trial.评价鼻腔压迫联合氨甲环酸与单纯鼻腔压迫和 Merocel 填塞治疗鼻出血的效果：一项随机对照试验。
Ann Emerg Med. 2019 Jul;74(1):72-78. doi: 10.1016/j.annemergmed.2019.03.030. Epub 2019 May 9.
Zotero 插件