Maiorca Carlo, Serriello Ilaria, Pettorini Laura, Taffon Chiara, Belli Marco, Cossetti Fatma, Di Matteo Rosaria, Londrino Francesco, Papalini Sandra, Propato Antonella, Tricerri Augusto, Zaccheo Cinzia, Magnanti Massimo
UOC Pronto Soccorso e Medicina d'Urgenza, P.O. San Filippo Neri, ASL Roma 1, Roma.
UOC Nefrologia e Dialisi, ASL Roma 1, Roma.
G Ital Nefrol. 2024 Oct 31;41(5):2024-vol5. doi: 10.69097/41-05-2024-06.
Antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV) primarily affects small- and medium-sized arteries, including kidney vessels, thus causing rapidly progressive glomerulonephritis. The pathogenesis of AAV is intricate and several factors, including infections, are known to possibly trigger the autoimmune process. Numerous studies have reported that SARS-CoV-2 might cause acute kidney injury (AKI). To date, a modest number of AAV with COVID-19 cases has been reported. Herein, we discuss the case of a 61-year-old man with new-onset of diffuse proliferative ANCA-associated glomerulonephritis after COVID-19.
抗中性粒细胞胞浆自身抗体（ANCA）相关血管炎（AAV）主要累及中小动脉，包括肾血管，从而导致快速进展性肾小球肾炎。AAV的发病机制复杂，已知包括感染在内的多种因素可能触发自身免疫过程。大量研究报告称，严重急性呼吸综合征冠状病毒2（SARS-CoV-2）可能导致急性肾损伤（AKI）。迄今为止，已报告了少量新冠肺炎合并AAV的病例。在此，我们讨论一例61岁男性在感染新冠肺炎后新发弥漫性增生性ANCA相关肾小球肾炎的病例。
