Department of Hematology, Dijon Bourgogne University Hospital and INSERM UMR 1231, Dijon, France.
Department of Hematology, university hospital of Rennes, Rennes, France.
Eur J Cancer. 2024 Dec;213:115073. doi: 10.1016/j.ejca.2024.115073. Epub 2024 Oct 22.
Classic Hodgkin lymphoma (HL) is a distinct entity among hematological malignancies of B-cell origin. It is characterized by its unique histopathological features and generally favorable prognosis. Over the years, advancements in understanding its pathogenesis, coupled with refined diagnostic and evaluation modalities, as well as therapeutic strategies, have significantly transformed the landscape of HL management. In this article, we present a comprehensive set of recommendations for the management of HL, encompassing various aspects of diagnosis, risk stratification, evaluation, and treatment. These recommendations are based on the latest evidence-based guidelines, expert consensus opinions, and clinical trial data, aiming to provide clinicians with a practical framework for delivering optimal care to patients with HL.
经典型霍奇金淋巴瘤（HL）是 B 细胞来源的血液恶性肿瘤中一种独特的实体瘤。其具有独特的组织病理学特征，一般预后良好。多年来，人们对其发病机制的认识不断深入，加上精细的诊断和评估方法以及治疗策略的发展，极大地改变了 HL 的管理格局。本文针对 HL 的管理提出了一套全面的建议，涵盖了诊断、风险分层、评估和治疗等各个方面。这些建议基于最新的循证指南、专家共识意见和临床试验数据，旨在为临床医生为 HL 患者提供最佳治疗提供实用框架。
