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巴西圣保罗州 HPV 疫苗接种状况的批判性评估。

A critical evaluation of the status of HPV vaccination in São Paulo State, Brazil.

机构信息

Faculdade de Ciências Farmacêuticas da Universidade Federal do Amazonas, Manaus, AM, Brazil; Programa de Pós graduação em Imunologia Básica e aplicada - PPGIBA - Universidade Federal do Amazonas, Manaus, Brasil.

Department of Obstetrics and Gynecology, Weill Cornel Medicine, New York, USA; Medicine Tropical Institute, Virology Laboratory ‒ LIM/52, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.

出版信息

Clinics (Sao Paulo). 2024 Nov 6;79:100526. doi: 10.1016/j.clinsp.2024.100526. eCollection 2024.

Abstract

UNLABELLED

Cervical cancer, whose well-recognized etiological agent is the Human Papillomavirus (HPV), is responsible for approximately 300,000 deaths worldwide, 80% of cases occurring in developing countries. In Brazil, 17,010 cases were expected, with 2,550 cases in São Paulo State, in 2023. The Papanicolaou test is the diagnostic method for the detection of precancerous lesions of the cervix, and HPV vaccination is now available for prevention.

MATERIALS AND METHODS

This is a descriptive and exploratory, retrospective investigation, carried out through analysis of data obtained from Brazilian Information Technology (DATASUS) of the Brazilian Federal Government: Cancer Information System (SISCAN), Brazilian National Immunization Program (PNI) and Mortality Information System (SIM). Electronic Library and data made available by the Government of the State of São Paulo.

RESULTS

The number of women in São Paulo State who underwent cytological examinations and histological tests for cervical cancer decreased between the Years 2013 and 2022.

CONCLUSION

The continuous increase in cervical cancer over the study period was probably due to the lack of adherence to the primary and secondary prevention opportunities offered by the Public Health Authorities.

摘要

目的:探讨分析宫颈癌的发病因素,为宫颈癌的防治提供参考依据。

方法:采用描述性和探索性的回顾性研究方法,通过对巴西联邦政府信息技术(DATASUS)、巴西国家免疫计划(PNI)和死亡率信息系统(SIM)等数据库中宫颈癌筛查数据进行分析。同时,还利用了电子图书馆和圣保罗州政府提供的数据资源。

结果:在研究期间,圣保罗州进行宫颈癌细胞学检查和组织学检查的女性人数呈下降趋势。

结论:可能是由于公共卫生机构未能充分利用初级和二级预防机会,导致宫颈癌的发病率持续上升。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3727/11570814/f47ef62f714c/gr1.jpg

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