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回肠膀胱造口术并发造口静脉曲张出血:一例罕见病例报告及文献复习

Stomal variceal haemorrhage in ileal conduit diversion: a rare case report and literature review.

作者信息

Xu Mingjie, Lin Yiwei, Shen Bohua, Chen Geming

机构信息

Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine Hangzhou, Zhejiang, China.

出版信息

Front Oncol. 2024 Oct 24;14:1440828. doi: 10.3389/fonc.2024.1440828. eCollection 2024.

Abstract

BACKGROUND

Radical cystectomy is typically recommended for managing bladder cancer, with ileal conduit diversion being a prevalent form of urinary diversion. Stomal variceal haemorrhage is a rare complication of ileal bladder diversion and poses diagnostic and therapeutic challenges that can escalate to life-threatening circumstances. Hepatic cirrhosis and cancer liver metastasis-induced portal hypertension are considered the main causes of stomal varices. However, the real-world expertise in the pathophysiology of, diagnostic approach to, and overall management strategy for stomal variceal haemorrhage in ileal conduit diversion is limited.

CASE PRESENTATION

Herein, we present a rare case of a 77-year-old man with bladder cancer who developed stomal variceal haemorrhage after undergoing radical cystectomy and ileal conduit urinary diversion. Imaging revealed that the peristomal varices communicated with the subcutaneous veins of the abdominal wall without apparent portal hypertension. Transhepatic coil embolization of bleeding stomal varices was successfully performed via a transhepatic antegrade approach. No complications or stomal variceal haemorrhage occurred during a 6-month follow-up period.

CONCLUSION

Transhepatic coil embolization may be considered an initial therapeutic option for patients who experience stomal variceal haemorrhage. Comprehensive management of underlying liver disease and portal hypertension is needed at follow-up visits. We describe successful experience with the precise treatment of this rare and atypical disease, conduct a thorough review of the pertinent literature, and deliberate on optimized diagnostic and therapeutic procedures.

摘要

背景

根治性膀胱切除术通常被推荐用于治疗膀胱癌,回肠导管改道术是一种常见的尿流改道方式。造口静脉曲张出血是回肠膀胱改道的一种罕见并发症,带来了诊断和治疗挑战,甚至可能升级为危及生命的情况。肝硬化和癌性肝转移引起的门静脉高压被认为是造口静脉曲张的主要原因。然而,关于回肠导管改道中造口静脉曲张出血的病理生理学、诊断方法及整体管理策略的实际专业知识有限。

病例介绍

在此,我们报告一例罕见病例,一名77岁的膀胱癌男性在接受根治性膀胱切除术和回肠导管尿流改道后发生造口静脉曲张出血。影像学检查显示,造口周围静脉曲张与腹壁皮下静脉相通,无明显门静脉高压。通过经肝顺行途径成功地对出血的造口静脉曲张进行了经肝线圈栓塞术。在6个月的随访期内未发生并发症或造口静脉曲张出血。

结论

对于发生造口静脉曲张出血的患者,经肝线圈栓塞术可被视为初始治疗选择。随访时需要对潜在的肝脏疾病和门静脉高压进行综合管理。我们描述了对这种罕见且非典型疾病的精确治疗的成功经验,对相关文献进行了全面回顾,并探讨了优化的诊断和治疗程序。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d668/11540816/1c33679d7f83/fonc-14-1440828-g001.jpg

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