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机器人二尖瓣手术的历史回顾与进展

A Historical Perspective and Update on Robotic Mitral Valve Surgery.

作者信息

Chartrain Amy, Trento Alfredo, Gill George, Emerson Dominic, Cheng Wen, Ramzy Danny, Chikwe Joanna

机构信息

Department of Cardiac Surgery, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

Department of Cardiac Surgery, UTHealth Houston, Houston, TX 77030, USA.

出版信息

J Clin Med. 2024 Oct 24;13(21):6375. doi: 10.3390/jcm13216375.

Abstract

: Minimally invasive techniques for mitral valve repair have evolved over the past thirty years and include mini-thoracotomies and the robotic platform. This study provides a historical perspective on minimally invasive mitral valve approaches and evaluates long-term outcomes of a large series of robotic mitral valve repairs. : A single-institution, prospectively maintained registry was used to evaluate robotic mitral valve repairs performed by four surgeons from 2005 to 2023. There were 1412 robotic mitral valve repairs performed during this time and stratified by the first 120 and subsequent patients. We evaluated operative outcomes and freedom from more than 2+ mitral regurgitation at five years as well as ten-year survival. : Of the 1412 robotic mitral valve repairs performed, 93.6% ( = 1322) were for degenerative disease. Compared to the first 120 patients, the subsequent patients had a significant reduction in cross-clamp time (112 (IQR = 103-130) versus 75 (IQR = 65-88) min) and cardiopulmonary bypass time (153.5 (IQR = 134.5-177.5) versus 116 (IQR = 103-136) min), and all with < 0.01. The majority of patients had posterior leaflet prolapse (65.6%, = 926). The repair rate was 98.1%, = 1385. Survival at ten-year follow-up for the patients included in the first 120 procedures was 91.5% (95% confidence interval (CI) = 86.4-96.6%) versus 92.8% (95% CI = 91.7-93.9%) for the patients who were in the latter group, = 0.58. Freedom from >2+ mitral regurgitation at 5 years was 97.0% (95% CI = 95.3-98.7%) for the patients in the first 120 procedures and 92.7% (95% CI = 91.5-93.9%), = 0.22, for those in the latter group. : The robotic platform offers an excellent durable repair for mitral regurgitation in our experience of over 1400 patients. The robotic platform for mitral valve repair offers a teachable and safe approach to mitral valve disease for patients.

摘要

二尖瓣修复的微创技术在过去三十年中不断发展,包括微创开胸手术和机器人平台技术。本研究提供了微创二尖瓣手术方法的历史视角,并评估了一系列大型机器人二尖瓣修复手术的长期结果。

使用单一机构前瞻性维护的登记册来评估2005年至2023年期间四位外科医生进行的机器人二尖瓣修复手术。在此期间共进行了1412例机器人二尖瓣修复手术,并根据前120例患者和随后的患者进行分层。我们评估了手术结果、五年时无中重度二尖瓣反流的情况以及十年生存率。

在进行的1412例机器人二尖瓣修复手术中,93.6%(n = 1322)是针对退行性疾病。与前120例患者相比,随后的患者在体外循环时间(112(四分位间距[IQR]=103 - 130)分钟对75(IQR = 65 - 88)分钟)和心肺转流时间(153.5(IQR = 134.5 - 177.5)分钟对116(IQR = 103 - 136)分钟)上有显著减少,且P均<0.01。大多数患者为后叶脱垂(65.6%,n = 926)。修复率为98.1%(n = 1385)。在前120例手术中纳入的患者在十年随访时的生存率为91.5%(95%置信区间[CI]=86.4 - 96.6%),而后一组患者为92.8%(95% CI = 91.7 - 93.9%),P = 0.58。前120例手术患者在5年时无中重度二尖瓣反流的比例为97.0%(95% CI = 95.3 - 98.7%),后一组患者为92.7%(95% CI = 91.5 - 93.9%),P = 0.22。

根据我们对1400多名患者的经验,机器人平台为二尖瓣反流提供了出色的持久修复效果。用于二尖瓣修复的机器人平台为患者提供了一种可传授且安全的二尖瓣疾病治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c720/11546677/cf3a8ee2f456/jcm-13-06375-g001.jpg

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