Suppr超能文献

300 例机器人辅助二尖瓣修复术:西达赛奈的经验。

Three hundred robotic-assisted mitral valve repairs: the Cedars-Sinai experience.

机构信息

Division of Cardiothoracic Surgery, Cedars-Sinai Medical Center, Los Angeles, Calif.

Division of Cardiothoracic Surgery, Cedars-Sinai Medical Center, Los Angeles, Calif.

出版信息

J Thorac Cardiovasc Surg. 2014 Jan;147(1):228-35. doi: 10.1016/j.jtcvs.2013.09.035. Epub 2013 Nov 4.

Abstract

OBJECTIVE

The study objective was to review our first 300 consecutive robotic-assisted mitral repairs performed from June 2005 to October 2012 and to compare the surgical outcomes of our previously reported initial 120 cases with the subsequent 180 procedures.

METHODS

Our initial 120 robotic-assisted mitral repairs were previously reported, and we now compare our early experience with the recent 180 consecutive procedures for a total of 300 robotic-assisted mitral repairs. There was no patient selection. Every patient in need of isolated mitral valve repair underwent this procedure. All patients received an annuloplasty band and 1 or more of the following: leaflet resection, secondary chordal transposition, or polytetrafluoroethylene neochordal replacement and edge-to-edge repair.

RESULTS

All 300 patients had preoperative echocardiographic findings of severe mitral regurgitation. There were no differences (P = not significant) between the initial and the recent cohorts for preoperative characteristics, including age (58.4 ± 10.5 years vs 59.9 years), female gender (35.8% vs 36.1%), ejection fraction (61.9% vs 60.6%), congestive heart failure (35.0% vs 36.7%), creatinine (0.94 mg/dL vs 0.98 mg/dL), and New York Heart Association class. The incidence of anterior and posterior leaflet prolapse was similar in both groups, whereas Barlow syndrome was higher in group 2 (5.8% vs 27.8%). There was 1 (0.33%) hospital mortality and no deaths in the last 180 cases. Overall, 8 patients (2.7%) required subsequent mitral valve replacement via a median sternotomy, 6 (5.0%) in the first group and 2 (1.1%) in the second group (P = .06). One patient in each group had mitral valve re-repair through a right mini-thoracotomy, and 1 patient in the first group required a mitral valve replacement via a mini-thoracotomy during the original procedure. Two of the 180 patients had documented cerebrovascular accident, but both fully recovered clinically. There was no cerebrovascular accident in the last 120 patients. Crossclamp times decreased from 116 minutes to 91 minutes in the second group despite starting a training program with a junior associate performing part of the procedure at the console in the last 100 cases. Post-pump echocardiograms showed no/trace mitral regurgitation in 86.1% of the last 180 patients and mild mitral regurgitation in 11.1%. Follow-up echocardiography for the last 180 patients from 1 month to more than 1 year showed no/trace mitral regurgitation in 64.6% of patients and mild mitral regurgitation in 23.1% of patients. Seven patients (10.8%) had moderate mitral regurgitation, and 1 patient (1.5%) had severe mitral regurgitation.

CONCLUSIONS

The majority of complications and reoperations occurred early in our experience, especially using the first-generation da Vinci robot (Intuitive Surgical Inc, Sunnyvale, Calif). The newer da Vinci Si HD system with the addition of an adjustable left atrial roof retractor together with increased experience has made robotic-assisted mitral repair of all types of degenerative mitral valve pathology reproducible. The training of young surgeons in a stepwise fashion in high-volume centers will help to avoid the complications encountered during the introduction of this technology.

摘要

目的

本研究旨在回顾我们从 2005 年 6 月至 2012 年 10 月连续完成的 300 例机器人辅助二尖瓣修复术,并比较我们之前报告的前 120 例手术与随后的 180 例手术的手术结果。

方法

我们之前报告了前 120 例机器人辅助二尖瓣修复术,现在将我们的早期经验与最近的 180 例连续手术进行比较,总共进行了 300 例机器人辅助二尖瓣修复术。没有患者选择。所有需要二尖瓣修复的患者都接受了这项手术。所有患者均接受了环缩带,并且进行了以下一项或多项操作:瓣叶切除、次级腱索转位、或聚四氟乙烯人工腱索置换和瓣叶对合修复。

结果

所有 300 例患者术前超声心动图均显示严重二尖瓣反流。在术前特征方面,初始组与最近组之间没有差异(P 无显著差异),包括年龄(58.4 ± 10.5 岁比 59.9 岁)、女性(35.8%比 36.1%)、射血分数(61.9%比 60.6%)、充血性心力衰竭(35.0%比 36.7%)、肌酐(0.94mg/dL 比 0.98mg/dL)和纽约心脏病协会(NYHA)心功能分级。两组患者的前瓣和后瓣脱垂发生率相似,而巴洛综合征在第 2 组中发生率更高(5.8%比 27.8%)。有 1 例(0.33%)院内死亡,最近 180 例中无死亡病例。总的来说,有 8 例(2.7%)患者需要通过正中胸骨切开术进行后续二尖瓣置换术,第 1 组中有 6 例(5.0%),第 2 组中有 2 例(1.1%)(P =.06)。第 1 组和第 2 组各有 1 例患者通过右侧小开胸进行二尖瓣再次修复,第 1 组中有 1 例患者在最初的手术中通过小开胸进行了二尖瓣置换术。180 例患者中有 2 例记录到脑血管意外,但均完全临床恢复。在最后 120 例患者中没有脑血管意外。尽管在最后 100 例手术中有一名初级助手在控制台协助部分手术,但第 2 组的体外循环时间从 116 分钟减少到 91 分钟。术后超声心动图显示最后 180 例患者中有 86.1%无/微量二尖瓣反流,11.1%有轻度二尖瓣反流。对最后 180 例患者的术后超声心动图随访 1 个月至 1 年以上,64.6%的患者无/微量二尖瓣反流,23.1%的患者有轻度二尖瓣反流。7 例(10.8%)患者有中度二尖瓣反流,1 例(1.5%)患者有重度二尖瓣反流。

结论

大多数并发症和再次手术发生在我们经验的早期,尤其是使用第一代达芬奇机器人(Intuitive Surgical Inc,加利福尼亚州森尼韦尔)。较新的达芬奇 Si HD 系统增加了可调节的左心房顶牵开器,同时增加了经验,使得所有类型的退行性二尖瓣瓣膜病变的机器人辅助二尖瓣修复术都具有可重复性。在高容量中心逐步培训年轻外科医生将有助于避免在引入这项技术时遇到的并发症。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验