DNA周围的抗衡离子分布：随构象和序列的变化
Counterion distribution around DNA: variation with conformation and sequence.
作者信息
Pack G R, Wong L, Prasad C V
出版信息
Nucleic Acids Res. 1986 Feb 11;14(3):1479-93. doi: 10.1093/nar/14.3.1479.
Abstract
The three-dimensional Poisson-Boltzmann equation for the distribution of counterion charge density around double helical DNA has been solved by an iterative procedure. These computations have been performed for 0.01M monovalent salt solutions. A systematic study of the ten possible sequences found among adjacent nucleotide base pairs is presented for the A, B, and C conformations of DNA. In addition, calculations of the electrostatic stabilities of these conformations of DNA allows for comparison of the charge accumulation around each of the three conformers.
摘要
通过迭代程序求解了双螺旋DNA周围抗衡离子电荷密度分布的三维泊松-玻尔兹曼方程。这些计算是针对0.01M单价盐溶液进行的。对DNA的A、B和C构象中相邻核苷酸碱基对间发现的十种可能序列进行了系统研究。此外，对这些DNA构象的静电稳定性计算能够比较三种构象中每一种周围的电荷积累情况。
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