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坏死性小肠结肠炎手术试验中极早产儿的呼吸结局

Respiratory Outcomes of Infants Born Extremely Preterm in the Necrotizing Enterocolitis Surgery Trial.

作者信息

DeMauro Sara B, Jensen Erik A, McDonald Scott A, Hintz Susan, Tyson Jon, Stevenson David K, Blakely Martin L

机构信息

Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

出版信息

J Pediatr. 2025 Feb;277:114391. doi: 10.1016/j.jpeds.2024.114391. Epub 2024 Nov 8.

Abstract

The multicenter Necrotizing Enterocolitis Surgery Trial compared initial peritoneal drainage with laparotomy among infants with extremely low birth weight and surgical necrotizing enterocolitis or intestinal perforation. In this post hoc analysis of trial data, initial drainage was associated with adverse respiratory outcomes, both in hospital and through 2 years corrected age.

摘要

多中心坏死性小肠结肠炎手术试验比较了极低出生体重且患有外科坏死性小肠结肠炎或肠穿孔的婴儿进行初始腹腔引流与剖腹手术的效果。在对试验数据的这项事后分析中,初始引流与不良呼吸结局相关,无论是在住院期间还是在矫正年龄2岁之前。

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