Department of Neurology, Mayo Clinic, Rochester, MN, USA.
Department of Neurology, Mayo Clinic, Rochester, MN, USA.
Neuroimaging Clin N Am. 2025 Feb;35(1):123-132. doi: 10.1016/j.nic.2024.08.004. Epub 2024 Sep 5.
Cerebrospinal fluid leaks are important to recognize because they can cause debilitating symptoms for patients and have life-threatening complications. Leakage of cerebrospinal fluid (CSF) from the subarachnoid space can occur at the cranial or spinal level, with distinct clinical presentations, diagnostic evaluations, and treatment modalities depending on the type and location of the leak. Spontaneous, traumatic, and iatrogenic spinal CSF leaks cause reduced intracranial CSF volume and the clinicoradiologic syndrome commonly called "intracranial hypotension". This review discusses the clinical presentations, etiologies, and risk factors of spinal and cranial CSF leaks.
脑脊液漏是需要识别的重要问题，因为它可能导致患者出现使人虚弱的症状，并产生危及生命的并发症。脑脊液（CSF）从蛛网膜下腔漏出可发生在颅部或脊柱水平，根据漏口的类型和位置，具有不同的临床表现、诊断评估和治疗方式。自发性、外伤性和医源性的脊柱 CSF 漏导致颅内 CSF 容量减少，并出现通常称为“颅内低血压”的临床影像学综合征。本文讨论了脊柱和颅部 CSF 漏的临床表现、病因和危险因素。
