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影响因素及季节效应与阻塞性睡眠呼吸暂停患者持续气道正压通气治疗依从性的关系

Affecting factors and seasonal effects on the continuous positive airway pressure adherence of patients with obstructive sleep apnea.

作者信息

Lee Jung Ju, Jang Bong Jin, Kwon Daeho, Kim Hyeyun

机构信息

Sleep Medicine Research Center, Department of Neurology, College of Medicine, Catholic Kwandong University International St. Mary's Hospital, Incheon 22711, Republic of Korea.

Department of Medical Business Administration, Daegu Haany University, 201, Daegudae-ro, Gyeongsan-si 38610, Republic of Korea.

出版信息

Heliyon. 2024 Oct 26;10(21):e39840. doi: 10.1016/j.heliyon.2024.e39840. eCollection 2024 Nov 15.

Abstract

Continuous positive airway pressure (CPAP) is the preferred treatment for obstructive sleep apnea (OSA), but adherence remains challenging. This study identifies factors influencing CPAP adherence, including the impact of Korea's four distinct seasons. A retrospective study of 650 patients with OSA and prescribed with CPAP was conducted at a single institution from January 2018 to December 2020, and the patients' answers on various sleep questionnaires, demographic and polysomnographic data, and when and whether they returned the CPAP devices were collected and analyzed. The sample population was divided into when and whether the CPAP device was returned to the institution and the average daily use of the CPAP device. Results show that treatment failure is high in the first 12 weeks. Moreover, patients with more severe sleep apnea tended to have severe OSA-related clinical symptoms and are more likely to adhere to the treatment. In this study show that the seasons did not affect CPAP adherence because of indoor environmental factors. However, results show that other patient factors, such as BMI, AHI, RDI, daytime drowsiness, mood changes, and other OSA-related symptoms, have greater effects on CPAP adherence than seasonal change. Initial positive experience is important to adapt to the CPAP, and for this reason, more active intervention by sleep physicians during the initial CPAP adaptation is necessary.

摘要

持续气道正压通气(CPAP)是阻塞性睡眠呼吸暂停(OSA)的首选治疗方法,但依从性仍然具有挑战性。本研究确定了影响CPAP依从性的因素,包括韩国四个不同季节的影响。2018年1月至2020年12月在一家机构对650例接受CPAP治疗的OSA患者进行了回顾性研究,收集并分析了患者在各种睡眠问卷上的回答、人口统计学和多导睡眠图数据,以及他们归还CPAP设备的时间和是否归还。样本人群根据CPAP设备是否归还给机构以及CPAP设备的日均使用情况进行划分。结果显示,前12周治疗失败率很高。此外,睡眠呼吸暂停更严重的患者往往有严重的OSA相关临床症状,并且更有可能坚持治疗。本研究表明,由于室内环境因素,季节并未影响CPAP依从性。然而,结果显示,其他患者因素,如BMI、AHI、RDI、日间嗜睡、情绪变化和其他OSA相关症状,对CPAP依从性的影响比季节变化更大。最初的积极体验对于适应CPAP很重要,因此,睡眠医生在CPAP初始适应期间进行更积极的干预是必要的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/901b/11550607/b6c31d5e6980/gr1.jpg

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