Neves Junior Jose Apolinário Silva, Fernandes Ana Paula Andrade, Tardelli Maria Angela, Yamashita Américo Massafuni, Moura Sônia Maria Pereira Guimarães Togeiro, Tufik Sérgio, Silva Helga Cristina Almeida da
Universidade Federal de São Paulo, Escola Paulista de Medicina, Department of Surgery, Discipline of Anesthesiology, Pain and Intensive Care, São Paulo SP, Brazil.
Universidade Federal de São Paulo, Escola Paulista de Medicina, Department of Psychobiology, Sleep and Respiratory Divisions, São Paulo SP, Brazil.
Arq Neuropsiquiatr. 2020 Sep;78(9):561-569. doi: 10.1590/0004-282X20200086.
Obstructive Sleep Apnea Syndrome (OSAS) is a public health problem of high prevalence and impacts on quality of life, anesthetic complications and cardiovascular diseases. In view of the difficulty in accessing the polysomnography, it is necessary to validate other methods for OSAS diagnostic screening in clinical practice in our country, such as the STOP-Bang questionnaire.
To validate the STOP-Bang questionnaire in Brazilians and evaluate optimal cutoff points.
After translation and back-translation, STOP-Bang questionnaire was applied to 71 individuals previously submitted to polysomnography and classified into control, mild, moderate or severe OSAS.
The majority of patients was male (59.2%), white (79%), aged 48.9±13.9 years, and with neck circumference >40 centimeters (73.8%). STOP-Bang score was higher in OSAS mild (median/inter-quartis 25-75%: 5/3.5-6), moderate (4.5/4-5) and severe (5/4-6), versus control (2.5/1-4). The receiver operating characteristic (ROC) curve indicate that scores 3, 4 and 6, present the best specificity values (100, 80 and 92.9%) with acceptable sensitivity (60, 66.7 and 50%) in the mild, moderate and severe OSAS subgroups, respectively. In OSAS group analysis (Apnea Hypopnea Index [AHI] ≥5, <15, ≥15 - <30, ≥30), STOP-Bang cutoff point of 6 was optimal to detect OSAS.
STOP-Bang Brazilian version identified OSAS patients with lower sensitivity and higher specificity compared to previous studies. Different cutoff points would improve the performance to detect patients with more severe OSAS.
阻塞性睡眠呼吸暂停综合征(OSAS)是一个具有高患病率的公共卫生问题,会影响生活质量、麻醉并发症和心血管疾病。鉴于多导睡眠图检查难以开展,有必要在我国临床实践中验证其他用于OSAS诊断筛查的方法,如STOP-Bang问卷。
在巴西人群中验证STOP-Bang问卷,并评估最佳截断点。
经过翻译和回译后,将STOP-Bang问卷应用于71名先前接受过多导睡眠图检查的个体,这些个体被分为对照组、轻度、中度或重度OSAS组。
大多数患者为男性(59.2%),白人(79%),年龄48.9±13.9岁,颈围>40厘米(73.8%)。与对照组(2.5/1-4)相比,轻度(中位数/四分位数间距25-75%:5/3.5-6)、中度(4.5/4-5)和重度(5/4-6)OSAS患者的STOP-Bang评分更高。受试者工作特征(ROC)曲线表明,在轻度、中度和重度OSAS亚组中,评分3、4和6分别具有最佳的特异性值(100%、80%和92.9%)以及可接受的敏感性(60%、66.7%和50%)。在OSAS组分析(呼吸暂停低通气指数[AHI]≥5、<15、≥15-<30、≥30)中,STOP-Bang截断点为6时最适合检测OSAS。
与先前的研究相比,巴西版STOP-Bang问卷识别OSAS患者的敏感性较低,但特异性较高。不同的截断点将提高检测更严重OSAS患者的效能。