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靛蓝、靛玉红和异靛蓝的糖苷:蓝色、红色和黄色糖类及其抗癌活性。

-Glycosides of indigo, indirubin, and isoindigo: blue, red, and yellow sugars and their cancerostatic activity.

作者信息

Langer Peter

机构信息

Institut für Chemie, Universität Rostock, Albert-Einstein-Str. 3a, 18059 Rostock, Germany.

出版信息

Beilstein J Org Chem. 2024 Nov 8;20:2840-2869. doi: 10.3762/bjoc.20.240. eCollection 2024.

Abstract

Indigo, indirubin, and isoindigo derivatives have been used for centuries as pigments. Since the 1990s, a new aspect of the chemistry of this type of compounds is their activity against various types of cancer. -Glycosides of indigo, indirubin, and isoindigo, blue, red, and yellow sugars, turned out to be of special interest because of their high cancerostatic activity and structural novelty. The present article provides an account on the synthesis and anticancer activity of these compounds.

摘要

靛蓝、靛玉红和异靛蓝衍生物作为颜料已被使用了几个世纪。自20世纪90年代以来,这类化合物化学的一个新方面是它们对各种类型癌症的活性。靛蓝、靛玉红和异靛蓝的糖苷,蓝色、红色和黄色糖类,因其高抗癌活性和结构新颖性而特别受关注。本文介绍了这些化合物的合成及抗癌活性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b39/11552416/614aa9c1fa15/Beilstein_J_Org_Chem-20-2840-g002.jpg

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