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医疗补助覆盖的连续性与儿童、青少年及青年成年人的淋巴瘤分期相关。

Medicaid coverage continuity is associated with lymphoma stage among children and adolescents/young adults.

作者信息

Zhang Xinyue Elyse, Castellino Sharon M, Yabroff K Robin, Stock Wendy, Cornwell Patricia, Bai Shasha, Mertens Ann C, Lipscomb Joseph, Ji Xu

机构信息

Department of Health Policy and Management, Emory University Rollins School of Public Health, Atlanta, GA.

Department of Pediatrics, Emory University School of Medicine, Atlanta, GA.

出版信息

Blood Adv. 2025 Jan 28;9(2):280-290. doi: 10.1182/bloodadvances.2024013532.

Abstract

Lymphoma is the third leading cause of cancer among children and adolescents/young adults (AYAs) in the United States, with later-stage diagnoses often being linked to worse outcomes. Continuous health insurance coverage is crucial for facilitating early cancer detection and diagnosis. Among Medicaid-insured children and AYAs diagnosed with lymphoma, this study examines whether the timing of Medicaid enrollment and coverage continuity are associated with stage at diagnosis. Using the Surveillance, Epidemiology, and End Results-Medicaid data, we identified children and AYAs (aged 0-39 years) newly diagnosed with lymphoma between 2007 and 2013 in 12 states that were linked to the administrative Medicaid data. Medicaid enrollment patterns were categorized into continuous Medicaid (preceding and through diagnosis), newly gained Medicaid (at or shortly after diagnosis), and other Medicaid enrollment patterns. Late-stage disease was defined as Ann Arbor stage IV (vs stage I-III). Multiple logistic regressions were estimated, with marginal effects (MEs) reported. Of 3524 patients identified, 37.8% had continuous Medicaid, followed by newly gained Medicaid (35.2%) and other Medicaid enrollment patterns (27.0%). Compared with patients continuously enrolled in Medicaid, those with newly gained Medicaid and with other Medicaid enrollment patterns were 54% (ME, 13.9 percentage points [ppt]; 95% confidence interval [CI], 8.5-19.2; P < .001) and 18% (ME, 4.6 ppt; 95% CI, 2.2-7.0; P < .001) more likely to present with stage IV lymphoma, respectively. Overall, having continuous Medicaid coverage before diagnosis was associated with a lower likelihood of late-stage lymphoma at diagnosis; however, only 3 in 8 Medicaid-insured children and AYAs with lymphoma were continuously enrolled in Medicaid before their diagnosis.

摘要

淋巴瘤是美国儿童和青少年/青年成人(AYAs)中第三大常见癌症,晚期诊断往往与较差的预后相关。持续的医疗保险覆盖对于促进癌症的早期检测和诊断至关重要。本研究调查了在医疗补助计划(Medicaid)参保的儿童和AYAs中,Medicaid参保时间和覆盖连续性是否与诊断时的分期有关。利用监测、流行病学和最终结果 - Medicaid数据,我们在12个与Medicaid行政数据相关联的州中,确定了2007年至2013年间新诊断为淋巴瘤的儿童和AYAs(年龄在0 - 39岁)。Medicaid参保模式分为持续参保Medicaid(诊断前及诊断期间)、新获得Medicaid(诊断时或诊断后不久)以及其他Medicaid参保模式。晚期疾病定义为Ann Arbor分期IV期(对比I - III期)。我们进行了多项逻辑回归分析,并报告了边际效应(MEs)。在3524名确定的患者中,37.8%有持续的Medicaid参保,其次是新获得Medicaid(35.2%)和其他Medicaid参保模式(27.0%)。与持续参保Medicaid的患者相比,新获得Medicaid和其他Medicaid参保模式的患者分别有54%(ME,13.9个百分点[ppt];95%置信区间[CI],8.5 - 19.2;P <.001)和18%(ME,4.6 ppt;95% CI,2.2 - 7.0;P <.001)的可能性被诊断为IV期淋巴瘤。总体而言,诊断前有持续的Medicaid覆盖与诊断时晚期淋巴瘤的可能性较低相关;然而,在8名有淋巴瘤的Medicaid参保儿童和AYAs中,只有3人在诊断前持续参保Medicaid。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b377/11786654/d77f7cded2a1/BLOODA_ADV-2024-013532-ga1.jpg

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