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治疗奶牛爪形趾病变的方法及其对运动评分、步态特性、病变进展和痛觉阈值的影响:系统评价。

Treatment modalities for claw horn lesions and their effects on locomotion scores, gait properties, lesion progression, and nociceptive threshold in dairy cows: A systematic review.

机构信息

Department of Farm and Exotic Animal Medicine and Surgery, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400 UPM Serdang, Malaysia.

Department of Farm and Exotic Animal Medicine and Surgery, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400 UPM Serdang, Malaysia.

出版信息

Res Vet Sci. 2024 Dec;181:105448. doi: 10.1016/j.rvsc.2024.105448. Epub 2024 Nov 7.

Abstract

This systematic review presents scientific evidence on treatment modalities for claw horn lesions (CHLs) in dairy cows, and their efficacy in restoring normal gait, resolution of claw lesions, and improving nociceptive threshold. A literature search was performed in four databases leading to the synthesis of 10 articles for the final analysis. The types of treatment administered include single (STM), bimodal (BTM) and multimodal treatment modalities (MTM). Locomotion scores (LS) were the most reported outcome measure, followed by the resolution of claw lesion, time to lameness cure, nociceptive threshold and gait properties. Most pairwise comparisons for LS and nociceptive threshold depicted no significant difference between the various treatment groups. Meanwhile, a few pairwise comparisons in terms of resolution of claw lesion and time to lameness cure revealed that cows receiving MTM (claw trimming + hoof block + NSAID) or BTM (claw trimming + hoof block) recorded complete resolution of CHL and significantly less time to recover compared to those treated with an STM (only claw trimming). Despite the various modalities used in CHL treatment, their effects on LS, nociceptive threshold, and gait properties are still unclear. While evidence suggests that MTM and BTM facilitate rapid resolution of CHL and duration of lameness cure, only limited data are available and the association with specific lesions is poorly understood. Several sources of heterogeneity were identified between the studies, particularly duration of follow-up after treatment, LS systems, severity and duration of lameness, and types of treatment administered.

摘要

本系统评价呈现了针对奶牛爪角病变(CHL)治疗方法的科学证据,以及这些方法在恢复正常步态、解决爪病变和提高疼痛阈值方面的疗效。在四个数据库中进行了文献检索,最终分析综合了 10 篇文章。所使用的治疗类型包括单一治疗模式(STM)、双模态治疗模式(BTM)和多模态治疗模式(MTM)。运动评分(LS)是最常报道的结果衡量指标,其次是爪病变的解决、跛行治愈时间、疼痛阈值和步态特性。LS 和疼痛阈值的大多数两两比较表明,不同治疗组之间没有显著差异。同时,在爪病变解决和跛行治愈时间方面的一些两两比较表明,接受 MTM(蹄修整+蹄块+NSAID)或 BTM(蹄修整+蹄块)治疗的奶牛记录到 CHL 完全解决,并且与仅接受 STM(仅蹄修整)治疗的奶牛相比,恢复时间显著缩短。尽管 CHL 治疗中使用了各种方法,但它们对 LS、疼痛阈值和步态特性的影响仍不清楚。虽然有证据表明 MTM 和 BTM 有助于快速解决 CHL 和跛行治愈时间,但可用的数据有限,并且与特定病变的关联理解有限。研究之间存在几个异质性来源,特别是治疗后随访的时间、LS 系统、跛行的严重程度和持续时间以及所使用的治疗类型。

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