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全身动脉循环中的基因共性。

Gene Commonality in Arterial Circuits Throughout the Body.

作者信息

Harling Lisa C, Zafar Mohammad A, Ziganshin Bulat, Elefteriades John A

机构信息

Aortic Institute at Yale New Haven, Yale Medicine Department of Surgery, Yale University, New Haven, Connecticut.

Otto von Guericke University Medical School, Magdeburg, Germany.

出版信息

Aorta (Stamford). 2024 Feb;12(1):8-12. doi: 10.1055/s-0044-1791667. Epub 2024 Nov 12.

Abstract

The common genetic underpinnings of thoracic aortic aneurysms and aneurysms and dissections of several other major arterial circuits have been described in the literature. These include thoracic and abdominal aortic aneurysms, thoracic and intracranial aneurysms, thoracic aortic aneurysms, and spontaneous coronary artery dissections. In this study, we provide a unified report of these observations and investigate any genetic commonality between the above four arterial circulations.

摘要

文献中已描述了胸主动脉瘤以及其他几个主要动脉循环的动脉瘤和夹层的常见遗传基础。这些包括胸主动脉瘤和腹主动脉瘤、胸主动脉瘤和颅内动脉瘤、胸主动脉瘤以及自发性冠状动脉夹层。在本研究中,我们提供了这些观察结果的统一报告,并研究了上述四种动脉循环之间的任何遗传共性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9e6/11606663/dd8c3226b179/10-1055-s-0044-1791667-i240008-1.jpg

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