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Int Nurs Rev. 2020 Dec;67(4):554-559. doi: 10.1111/inr.12632. Epub 2020 Oct 2.
2
Time in the Therapeutic Range (TTR): An Overly Simplified Conundrum.治疗范围内时间（TTR）：一个过度简化的难题。
J Innov Card Rhythm Manag. 2017 Mar 15;8(3):2643-2646. doi: 10.19102/icrm.2017.080302. eCollection 2017 Mar.
3
Does a complex intervention increase patient knowledge about oral anticoagulation? - a cluster-randomised controlled trial.一项复杂干预措施能否增加患者对抗凝治疗的了解？一项整群随机对照试验。
BMC Fam Pract. 2017 Feb 7;18(1):15. doi: 10.1186/s12875-017-0588-2.
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[Proposal to improve the sustainability of the public health system from the framework of nursing competence].
Enferm Clin. 2015 May-Jun;25(3):149-50. doi: 10.1016/j.enfcli.2015.01.001. Epub 2015 Apr 16.
5
[Anticoagulant therapy clinic: moving towards Advanced Nursing Practice].抗凝治疗诊所：迈向高级护理实践
Enferm Clin. 2014 May-Jun;24(3):200-4. doi: 10.1016/j.enfcli.2014.02.002. Epub 2014 Apr 18.
6
Two monitoring methods of oral anticoagulant therapy in patients with mechanical heart valve prothesis: a meta-analysis.两种机械心脏瓣膜置换术后患者口服抗凝治疗监测方法的荟萃分析。
J Thromb Thrombolysis. 2012 Jan;33(1):38-47. doi: 10.1007/s11239-011-0626-1.
7
Evaluation of patients' knowledge on warfarin in outpatient anticoagulation clinics in a teaching hospital in Qatar.卡塔尔一家教学医院门诊抗凝诊所患者对华法林知识的评估。
Saudi Med J. 2010 Jun;31(6):672-7.
8
The development and performance validation of a tool to assess patient anticoagulation knowledge.一种评估患者抗凝知识工具的开发与性能验证
Res Social Adm Pharm. 2005 Mar;1(1):40-59. doi: 10.1016/j.sapharm.2004.12.002.
9
Long-term, low-intensity warfarin therapy for the prevention of recurrent venous thromboembolism.长期、低强度华法林治疗预防复发性静脉血栓栓塞。
N Engl J Med. 2003 Apr 10;348(15):1425-34. doi: 10.1056/NEJMoa035029. Epub 2003 Feb 24.
10
Patient self-management of chronic disease in primary care.基层医疗中慢性病的患者自我管理
JAMA. 2002 Nov 20;288(19):2469-75. doi: 10.1001/jama.288.19.2469.

[提高自我监测抗凝患者知识水平及治疗范围的教育项目]

[Educational program to improve knowledge and therapeutic range for self-controlled anticoagulated patients].

作者信息

Romero-Arana Adolfo, González-Rodríguez María José, Sánchez-Vega Patricia, García-Iglesias Juan Jesús, Gómez-Salgado Juan, Romero Adolfo

机构信息

Servicio Andaluz de Salud, Distrito Sanitario Costa del Sol, Málaga, España; Instituto de Investigaciones Biomédicas de Málaga (IBIMA-Bionand), Málaga, España.

Unidad de Tratamiento Anticoagulante, Hospital Valle del Guadalhorce, Cártama, Málaga, España.

出版信息

Aten Primaria. 2025 May;57(5):103139. doi: 10.1016/j.aprim.2024.103139. Epub 2024 Nov 12.

DOI:10.1016/j.aprim.2024.103139
PMID:39536414
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11605452/
Abstract

INTRODUCTION

Oral anticoagulation Self-control programs have demonstrated efficiency over recent years.

OBJECTIVE

The aim of the study was to evaluate the level of knowledge and coagulation level of self-controlled anticoagulated patients after an educational program.

DESIGN

A quasi-experimental study, pre-test and post-test. SITE: Health area of the Hematology Service of the Virgen de la Victoria University Hospital (Málaga, Spain).

PARTICIPANTS

Self-monitored anticoagulated patients.

INTERVENTIONS

Educational intervention about oral anticoagulation knowledge focused on patients that will initiate the self-control program in our consultation.

MAIN MEASUREMENTS

To check the patient's adherence and coagulation level, we evaluated the Rosendaal Time in Therapeutic Rank (TTRr), both before and after the intervention.

RESULTS

145 patients have been included from 2016 to 2022 with a mean age of 49.18 years (SD 17.24). The mean score for the first test about knowledge was 14.61 (SD 3.26) and the mean score for the second test was 17.01 (SD 2.14) (p <0.001). Values before and after interventions were also statistically significant (67.46 vs 70.53, p<0.001).

CONCLUSIONS

The results showed that knowledge improved after the training session and the TTR values are better after the training which appears to be an effective action to improve the knowledge about oral anticoagulation in these patients.

摘要

引言

近年来，口服抗凝自我管理项目已证明具有有效性。

目的

本研究旨在评估教育项目后自我管理抗凝患者的知识水平和凝血水平。

设计

一项准实验性研究，包括前测和后测。地点：维多利亚圣母大学医院血液科的健康区域（西班牙马拉加）。

参与者

自我监测的抗凝患者。

干预措施

针对将在我们的门诊开始自我管理项目的患者，开展关于口服抗凝知识的教育干预。

主要测量指标

为检查患者的依从性和凝血水平，我们在干预前后评估了治疗排名中的罗森达尔时间（TTRr）。

结果

2016年至2022年纳入了145名患者，平均年龄为49.18岁（标准差17.24）。第一次知识测试的平均得分为14.61（标准差3.26），第二次测试的平均得分为17.01（标准差2.14）（p<0.001）。干预前后的值也具有统计学意义（67.46对70.53，p<0.001）。

结论

结果表明，培训后知识水平有所提高，培训后TTR值更好，这似乎是提高这些患者口服抗凝知识的有效举措。