Vogelweid C M, Miller R B, Berg J N, Kinden D A
Am J Vet Res. 1986 Feb;47(2):378-84.
Effects of UV radiation and irradiation followed by challenge exposure with Moraxella bovis on the corneal epithelium were studied in 6 calves by scanning electron microscopy. After UV irradiation, the number of dark cells comprising the surface epithelium increased. Many epithelial cells were in various states of degeneration and were characterized initially by large round nuclei, whereas sloughing and peeling were characteristic of the last degenerative stage. All M bovis-infected irradiated eyes had large numbers of degenerating cells, deep epithelial defects, fibrin strands, surface inflammatory cells, and debris. A few M bovis organisms were randomly attached to the cornea before visible ulceration. There were many inflammatory cells between the ulcerated corneal epithelium and adjacent nonulcerated epithelium. Epithelial cells at the margin of the ulcer appeared swollen. Light, dark, and intermediate epithelial cell types could not be distinguished peripheral to the ulcer.
通过扫描电子显微镜对6头小牛进行研究，观察紫外线辐射以及随后用牛莫拉菌进行激发暴露对角膜上皮的影响。紫外线照射后，构成表面上皮的暗细胞数量增加。许多上皮细胞处于不同的退化状态，最初的特征是圆形大细胞核，而脱落和剥离是最后退化阶段的特征。所有感染牛莫拉菌的照射眼都有大量退化细胞、深层上皮缺损、纤维蛋白丝、表面炎性细胞和碎屑。在可见溃疡形成之前，少数牛莫拉菌随机附着于角膜。溃疡角膜上皮与相邻未溃疡上皮之间有许多炎性细胞。溃疡边缘的上皮细胞出现肿胀。在溃疡周边无法区分明细胞、暗细胞和中间型上皮细胞类型。
