Department of Medicine, Chicago Medical School, Rosalind Franklin University of Medicine and Science, 3333 Green Bay Road, North Chicago, IL 60064, USA.
Department of Dermatology, Gold Skin Care Center, 2000 Richard Jones Road, Suite 220, Nashville, TN 37215, USA.
Dermatol Clin. 2025 Jan;43(1):55-66. doi: 10.1016/j.det.2024.08.004. Epub 2024 Oct 20.
This study aims to analyze and discuss recent trials of high-dose and liquid toxins for treating moderate to severe glabellar lines. A comprehensive review of clinical studies and patient outcomes data was conducted to assess the effectiveness and safety profiles of high-dose and liquid toxins. Clinical studies have demonstrated that high-dose toxins provide prolonged muscle relaxation and reduced wrinkles, with well-tolerated safety profiles. Liquid toxins offer comparable efficacy to traditional formulations with quicker onset and extended duration of effects. The introduction of high-dose and liquid toxins represents a significant advancement in esthetic medicine, providing patients with more options for achieving natural-looking, long-lasting results.
本研究旨在分析和讨论高剂量和液体毒素治疗中重度眉间纹的近期临床试验。通过对临床研究和患者结局数据的全面回顾，评估了高剂量和液体毒素的有效性和安全性特征。临床研究表明，高剂量毒素可提供更持久的肌肉松弛和减少皱纹，具有良好的安全性。液体毒素与传统制剂具有相似的疗效，起效更快，作用持续时间更长。高剂量和液体毒素的引入代表了美容医学的重大进展，为患者提供了更多选择，以实现自然、持久的效果。
