Poole G V, Albertson D A, Myers R T
Am Surg. 1986 Mar;52(3):170-3.
Serum parathormone (PTH) values are believed useful in diagnosing hyperparathyroidism and in evaluating patients before parathyroid operation. From 1975 through 1983, 328 adults patients with persistent hypercalcemia and normal renal function underwent cervical exploration for presumed primary hyperparathyroidism. Preoperative serum PTH values were obtained in 137 patients. Eight had negative explorations (5.8%): serum PTH values were normal in three patients and elevated in five. Serum PTH values were normal or low in 31 of the other 129 patients (false-negative rate = 24%). Of 191 patients for whom neither serum PTH nor nephrogenic cyclic adenosine-3',5'-monophosphate values did not were obtained preoperatively serum PTH values did not reduce the incidence of negative cervical explorations and, when obtained, they were misleading in one fourth of patients who benefitted from parathyroid exploration.
血清甲状旁腺激素（PTH）值被认为对诊断甲状旁腺功能亢进以及在甲状旁腺手术前评估患者有用。1975年至1983年期间，328例持续性高钙血症且肾功能正常的成年患者因疑似原发性甲状旁腺功能亢进接受了颈部探查。137例患者获得了术前血清PTH值。8例探查结果为阴性（5.8%）：3例患者血清PTH值正常，5例升高。其他129例患者中有31例血清PTH值正常或偏低（假阴性率 = 24%）。在191例术前未获得血清PTH值和肾源性环磷酸腺苷值的患者中，血清PTH值并未降低颈部探查阴性的发生率，而且在接受甲状旁腺探查受益的患者中，有四分之一的患者其血清PTH值会产生误导。
