Hruza G J, Kerdel F A
Arch Dermatol. 1986 Mar;122(3):320-2.
A 53-year-old man presented to the Manhattan (NY) Veterans Administration Hospital with a 20-year history of generalized atrophic lesions associated with lower extremity ulcerations. Cutaneous biopsy specimens and other laboratory data confirmed the diagnosis of sarcoidosis involving the skin, lungs, eyes, joints, bones, pituitary gland, gonads, and liver. To our knowledge, generalized atrophic sarcoidal lesions have not been described previously in the English literature. Ulcerated cutaneous sarcoidal lesions, though recognized, are only rarely seen in the disease. The ulcerations, but not the atrophic lesions, responded to prednisone therapy.
一名53岁男性因全身性萎缩性病变伴下肢溃疡20年，就诊于纽约曼哈顿退伍军人管理局医院。皮肤活检标本及其他实验室检查结果确诊为结节病，累及皮肤、肺、眼、关节、骨骼、垂体、性腺及肝脏。据我们所知，英文文献中此前尚未描述过全身性萎缩性结节病损。溃疡性皮肤结节病损虽已被认识，但在该病中极为罕见。溃疡对泼尼松治疗有反应，但萎缩性病变无反应。
