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Molecular Insight into the Role of HLA Genotypes in Immunogenicity and Secondary Refractoriness to Anti-TNF Therapy in IBD Patients.对HLA基因型在炎症性肠病患者免疫原性及抗TNF治疗继发性难治性中作用的分子洞察
Int J Mol Sci. 2025 Jul 28;26(15):7274. doi: 10.3390/ijms26157274.

本文引用的文献

1
HLA-DQA1*05 Associates With Anti-Tumor Necrosis Factor Immunogenicity and Low Adalimumab Trough Concentrations in Inflammatory Bowel Disease Patients From the SERENE Ulcerative Colitis and Crohn's Disease Studies.来自SERENE溃疡性结肠炎和克罗恩病研究的炎症性肠病患者中，HLA-DQA1*05与抗肿瘤坏死因子免疫原性及阿达木单抗低谷浓度相关。
J Crohns Colitis. 2025 Jan 11;19(1). doi: 10.1093/ecco-jcc/jjae129.
2
Underpowered PANTS: A Response to the Conclusions of "Extended Analysis Identifies Drug-Specific Association of Two Distinct HLA Class II Haplotypes for Development of Immunogenicity to Adalimumab and Infliximab".效力不足的 PANTS：对“扩展分析确定两种不同 HLA II 类单倍型与阿达木单抗和英夫利昔单抗免疫原性发展的药物特异性关联”结论的回应
Gastroenterology. 2021 Jan;160(1):470-471. doi: 10.1053/j.gastro.2020.05.102. Epub 2020 Oct 3.
3
Extended Analysis Identifies Drug-Specific Association of 2 Distinct HLA Class II Haplotypes for Development of Immunogenicity to Adalimumab and Infliximab.扩展分析确定了与阿达木单抗和英夫利昔单抗免疫原性发展相关的2种不同HLA II类单倍型的药物特异性关联。
Gastroenterology. 2020 Aug;159(2):784-787. doi: 10.1053/j.gastro.2020.03.073. Epub 2020 Apr 8.

Association of the HLA-DQA1*05 Allelic Gene Variants with Immunogenicity to Anti-TNF therapeutics-Important Differences Between Infliximab and Adalimumab.

作者信息

Ternette Nicola, Liao Hanqing, Satsangi Jack

机构信息

School of Life Sciences, University of Dundee, Dundee, UK.

Nuffield Department of Medicine, University of Oxford, Oxford, UK.

出版信息

J Crohns Colitis. 2025 Apr 4;19(4). doi: 10.1093/ecco-jcc/jjae172.

DOI:10.1093/ecco-jcc/jjae172
PMID:39548751
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12001328/
Abstract
摘要