Department of Medicine, Harvard Combined Dermatology Residency; Department of Dermatology, Harvard Combined Dermatology Residency; Department of Medicine, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
Division of Rheumatology, Inflammation and Immunity, Department of Medicine, Brigham and Women's Hospital, 60 Fenwood Road, Boston, MA 02115, USA.
Rheum Dis Clin North Am. 2025 Feb;51(1):61-73. doi: 10.1016/j.rdc.2024.09.007. Epub 2024 Oct 11.
Coronavirus disease 2019 (COVID-19) vaccine uptake among individuals with rheumatic conditions remains low despite heightened risk for related adverse outcomes. This is especially pronounced among historically marginalized populations who suffered disproportionately from the COVID-19 pandemic. Among the myriad of reasons for low vaccine uptake, mistrust in the healthcare system, misinformation related to the vaccine development process, fear of rheumatic disease flares, and inconsistent physician recommendations, are highlighted. Two randomized controlled trials are underway leveraging multimodal strategies and community partnerships to disseminate COVID-19 vaccine information, reduce hesitancy and hopefully improve vaccine uptake, particularly in marginalized communities.
尽管患有风湿性疾病的个体面临与相关不良结局相关的更高风险，但他们对接种 2019 冠状病毒病（COVID-19）疫苗的接受程度仍然较低。在历史上处于边缘地位的人群中，这种情况尤为明显，他们不成比例地受到 COVID-19 大流行的影响。在疫苗接种率低的众多原因中，突出的有对医疗保健系统的不信任、与疫苗开发过程相关的错误信息、对风湿性疾病发作的恐惧以及医生建议不一致等。目前正在进行两项随机对照试验，利用多模式策略和社区伙伴关系来传播 COVID-19 疫苗信息，减少犹豫，并有望提高疫苗接种率，特别是在边缘社区。
